Papers - Furukawa, Yoshiaki

A molecular mechanism realizing sequence-specific recognition of nucleic acids by TDP-43

Furukawa, Yoshiaki, Suzuki, Yoh, Fukuoka, Mami, Nagasawa, Kenichi, Nakagome, Kenta, Shimizu, Hideaki, Mukaiyama, Atsushi, Akiyama, Shuji

SCIENTIFIC REPORTS 6   4144 - 4155 2016.02

Research paper (scientific journal),  ISSN  2045-2322

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Close Up実験法 Series258 タンパク質を再現性よく凝集させるコツ

古川良明

実験医学 ((株)羊土社)  33 ( 1 ) 93 - 97 2015.01

ISSN  0288-5514

神経・非神経細胞ネットワークと脳内環境 13.筋萎縮性側索硬化症におけるタンパク質の線維化とシーディング現象

古川良明

遺伝子医学MOOK  ( 26 ) 153 - 157 2014.11

ISSN  1349-2527

A Primary Role for Disulfide Formation in the Productive Folding of Prokaryotic Cu,Zn-superoxide Dismutase

Yasuyuki Sakurai, Itsuki Anzai, Yoshiaki Furukawa

JOURNAL OF BIOLOGICAL CHEMISTRY 289 ( 29 ) 20139 - 20149 2014.07

Accepted,  ISSN  0021-9258

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A seeded propagation of Cu, Zn-superoxide dismutase aggregates in amyotrophic lateral sclerosis

Mariko Ogawa, Yoshiaki Furukawa

FRONTIERS IN CELLULAR NEUROSCIENCE 8   83 2014.03

Accepted,  ISSN  1662-5102

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Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis

Takao Nomura, Shoji Watanabe, Kumi Kaneko, Koji Yamanaka, Nobuyuki Nukina, Yoshiaki Furukawa

JOURNAL OF BIOLOGICAL CHEMISTRY 289 ( 2 ) 1192 - 1202 2014.01

Accepted,  ISSN  0021-9258

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Redox environment is an intracellular factor to operate distinct pathways for aggregation of Cu,Zn-superoxide dismutase in amyotrophic lateral sclerosis

Yoshiaki Furukawa

FRONTIERS IN CELLULAR NEUROSCIENCE 7   240 2013.11

Accepted,  ISSN  1662-5102

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Functional diversity of protein fibrillar aggregates from physiology to RNA granules to neurodegenerative diseases

Yoshiaki Furukawa, Nobuyuki Nukina

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1832 ( 8 ) 1271 - 1278 2013.08

Accepted,  ISSN  0925-4439

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Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis

Yoshiaki Furukawa, Kumi Kaneko, Shoji Watanabe, Koji Yamanaka, Nobuyuki Nukina

FEBS LETTERS 587 ( 16 ) 2500 - 2505 2013.08

Accepted,  ISSN  0014-5793

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Disulfide scrambling describes the oligomer formation of superoxide dismutase (SOD1) proteins in the familial form of amyotrophic lateral sclerosis

Keisuke Toichi, Koji Yamanaka, Yoshiaki Furukawa

Journal of Biological Chemistry 288 ( 7 ) 4970 - 4980 2013.02

Accepted,  ISSN  0021-9258

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Post-aggregation Oxidation of Mutant Huntingtin Controls the Interactions between Aggregates

Yasushi Mitomi, Takao Nomura, Masaru Kurosawa, Nobuyuki Nukina, Yoshiaki Furukawa

JOURNAL OF BIOLOGICAL CHEMISTRY 287 ( 41 ) 34764 - 34775 2012.10

Accepted,  ISSN  0021-9258

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Local Unfolding of Cu, Zn Superoxide Dismutase Monomer Determines the Morphology of Fibrillar Aggregates

Feng Ding, Yoshiaki Furukawa, Nobuyuki Nukina, Nikolay V. Dokholyan

JOURNAL OF MOLECULAR BIOLOGY 421 ( 4-5 ) 548 - 560 2012.08

Accepted,  ISSN  0022-2836

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Pathological roles of wild-type Cu, Zn-superoxide dismutase in amyotrophic lateral sclerosis

Yoshiaki Furukawa

Neurology Research International 2012   323261 2012

Accepted,  ISSN  2090-1852

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Molecular properties of TAR DNA binding protein-43 fragments are dependent upon its cleavage site

Yoshiaki Furukawa, Kumi Kaneko, Nobuyuki Nukina

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1812 ( 12 ) 1577 - 1583 2011.12

Accepted,  ISSN  0925-4439

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Tau Protein Assembles into Isoform- and Disulfide-dependent Polymorphic Fibrils with Distinct Structural Properties

Yoshiaki Furukawa, Kumi Kaneko, Nobuyuki Nukina

JOURNAL OF BIOLOGICAL CHEMISTRY 286 ( 31 ) 27236 - 27246 2011.08

Accepted,  ISSN  0021-9258

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A Seeding Reaction Recapitulates Intracellular Formation of Sarkosyl-insoluble Transactivation Response Element (TAR) DNA-binding Protein-43 Inclusions

Yoshiaki Furukawa, Kumi Kaneko, Shoji Watanabe, Koji Yamanaka, Nobuyuki Nukina

JOURNAL OF BIOLOGICAL CHEMISTRY 286 ( 21 ) 18664 - 18672 2011.05

Accepted,  ISSN  0021-9258

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Mutation-dependent Polymorphism of Cu,Zn-Superoxide Dismutase Aggregates in the Familial Form of Amyotrophic Lateral Sclerosis

Yoshiaki Furukawa, Kumi Kaneko, Koji Yamanaka, Nobuyuki Nukina

JOURNAL OF BIOLOGICAL CHEMISTRY 285 ( 29 ) 22221 - 22231 2010.07

Accepted,  ISSN  0021-9258

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Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction

Tomoyuki Yamanaka, Asako Tosaki, Haruko Miyazaki, Masaru Kurosawa, Yoshiaki Furukawa, Mizuki Yamada, Nobuyuki Nukina

HUMAN MOLECULAR GENETICS 19 ( 11 ) 2099 - 2112 2010.06

Accepted,  ISSN  0964-6906

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Cross-Seeding Fibrillation of Q/N-Rich Proteins Offers New Pathomechanism of Polyglutamine Diseases

Yoshiaki Furukawa, Kumi Kaneko, Gen Matsumoto, Masaru Kurosawa, Nobuyuki Nukina

JOURNAL OF NEUROSCIENCE 29 ( 16 ) 5153 - 5162 2009.04

Accepted,  ISSN  0270-6474

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Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis

Yoshiaki Furukawa, Kumi Kaneko, Koji Yamanaka, Thomas V. O'Halloran, Nobuyuki Nukina

JOURNAL OF BIOLOGICAL CHEMISTRY 283 ( 35 ) 24167 - 24176 2008.08

Accepted,  ISSN  0021-9258

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