Presentations -
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Clinical and neuropathological study of an autopsied case of familial ALS with SOD1 mutation with very long survival
Yo-ichi Takei, Kenya Oguchi, Takaaki Miyahira, Akiyo Hineo, Akinori Nakamura, Shinji Ohara, and Yoshiaki Furukawa
[International presentation] The 68th Annual Meeting of the American Academy of Neurology (Vancouver, Canada) ,
2016.04,Poster presentation
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銅・亜鉛スーパーオキサイドディスムターゼの金属イオン結合状態を識別できる新規抗体の開発と筋萎縮性側索硬化症の病理解明への応用
徳田 栄一、森崎 祐太、三澤 日出巳、渡邊 征爾、山中 宏二、古川 良明
[Domestic presentation] 日本薬学会第136年会 (神奈川県・横浜市) ,
2016.03,Oral presentation (general)
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タンパク質の熱変性を通じて理解する神経変性疾患の発症メカニズム
安齋 樹、向山 厚、秋山 修志、古川 良明
[Domestic presentation] 日本化学会第96春季年会 (京都府・京田辺市) ,
2016.03,Oral presentation (general)
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細胞内銅イオン輸送を可能にする銅シャペロンのドメイン構造
福岡 真実、長野 功、古川 良明
[Domestic presentation] 日本化学会第96春季年会 (京都府・京田辺市) ,
2016.03,Oral presentation (general)
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抗酸化酵素の活性発現を可能にする金属イオンの新たな獲得メカニズム
小久保 鉄平、櫻井 靖之、古川 良明
[Domestic presentation] 日本化学会第96春季年会 (京都府・京田辺市) ,
2016.03,Oral presentation (general)
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筋萎縮性側索硬化症に見られるタンパク質ミスフォールディングのメカニズム
古川 良明
構造神経病理セミナー (京都府・京田辺市) ,
2016.03,Public lecture, seminar, tutorial, course, or other speech
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Protein conformational disorder leading to neurodegenerative diseases
FURUKAWA Yoshiaki
The 3rd Mini-Symposium on Cutting-Edge Chemistry (Hsinchu, Taiwan) ,
2016.03,Oral presentation (invited, special)
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Lost in metallation: the disaster on a protein structure leading to neurodegeneration
Yoshiaki Furukawa, Itsuki Anzai, Kennichi Nagasawa, Shuji Akiyama, Mizue Imai, and Koichiro Ishimori
[International presentation] 2015 International Chemical Congress of Pacific Basin Societies (Honolulu, USA) ,
2015.12,Oral presentation (general)
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Misregulation of thiol-disulfide status in Cu,Zn-superoxide dismutase with mutations causing amyotrophic lateral sclerosis
Yoshiaki Furukawa, Itsuki Anzai, Mariko Ogawa, and Eiichi Tokuda
[International presentation] The 1st International Symposium of Brain Protein Aging and Dementia Control (愛知県・名古屋市) ,
2015.10,Symposium, workshop panel (public)
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Physical property change associated with fibril formation of ALS-causative SOD1
Noriko Fujiwara, Michiru Wagatsuma, Daisaku Yoshihara, Yoshiaki Furukawa, Haruhiko Sakiyama, Hironobu Eguchi, and Keiichiro Suzuki
[Domestic presentation] 日本生物物理学会第53回年会 (石川県・金沢市) ,
2015.09,Poster presentation
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A mechanism describing pathological oligomerization of SOD1 in a budding yeast model
Kyohei Onose, Yuko Nishiura, and Yoshiaki Furukawa
[Domestic presentation] 日本生物物理学会第53回年会 (石川県・金沢市) ,
2015.09,Oral presentation (general)
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A new mechanism of SOD1 activation regulated by copper chaperone in Clonorchis sinensis
Mami Fukuoka, Isao Nagano, and Yoshiaki Furukawa
[Domestic presentation] 日本生物物理学会第53回年会 (石川県・金沢市) ,
2015.09,Oral presentation (general)
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A new peptide-based method to detect misfolded SOD1 proteins
Kenichi Nagasawa, Takao Nomura, and Yoshiaki Furukawa
[Domestic presentation] 日本生物物理学会第53回年会 (石川県・金沢市) ,
2015.09,Oral presentation (general)
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A new intramolecular route to acquire metal ions in superoxide dismutase
Teppei Kokubo, Yasuyuki Sakurai, and Yoshiaki Furukawa
[Domestic presentation] 日本生物物理学会第53回年会 (石川県・金沢市) ,
2015.09,Oral presentation (general)
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銅・亜鉛スーパーオキシドディスムターゼの光と影：抗酸化機能と神経変性疾患
古川 良明
第２８回生物無機化学夏季セミナー (静岡県伊東市) ,
2015.08,Public lecture, seminar, tutorial, course, or other speech
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Lights and shadows of Cu,Zn-superoxide dismutase
FURUKAWA Yoshiaki
[International presentation] The 17th International Conference on Biological Inorganic Chemistry (Beijing, China) ,
2015.07,Oral presentation (invited, special)
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Fungal isolates with different pathotypes show distinct levels of SOD1 activity controlled by copper chaperone
Carolyn Lim, Yoshiyuki Usami, and Yoshiaki Furukawa
[International presentation] The 17th International Conference on Biological Inorganic Chemistry (Beijing, China) ,
2015.07,Poster presentation
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Oligomerization of Cu,Zn-superoxide dismutase triggered by removal of metal ions and its pathological significance
Itsuki Anzai and Yoshiaki Furukawa
[International presentation] RIKEN Symposium “Metals in Biology in Wako” (埼玉県・和光市) ,
2015.06,Poster presentation
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Fungal isolates with different pathotypes show distinct levels of SOD1 activity controlled by copper chaperone
Carolyn Lim and Yoshiaki Furukawa
[International presentation] RIKEN Symposium “Metals in Biology in Wako” (埼玉県・和光市) ,
2015.06,Poster presentation
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A new intramolecular route for metal binding in Cu,Zn-superoxide dismutase
Teppei Kokubo and Yoshiaki Furukawa
[International presentation] RIKEN Symposium “Metals in Biology in Wako” (埼玉県・和光市) ,
2015.06,Poster presentation
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神経変性疾患に関連した異常なタンパク質オリゴマーの形成メカニズム
安齋 樹、向山 厚、秋山 修志、古川 良明
[Domestic presentation] 第42回生体分子科学討論会 (群馬県・高崎市) ,
2015.06,Oral presentation (general)
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Lim Carolyn T., Furukawa Yoshiaki
Seibutsu Butsuri,
2014,The Biophysical Society of Japan General Incorporated Association
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Ogawa Mariko, Shidara Hisashi, Oka Kotaro, Furukawa Yoshiaki
Seibutsu Butsuri,
2014,The Biophysical Society of Japan General Incorporated Association
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Nomura Takao, Watanabe Shoji, Kaneko Kumi, Yamanaka Koji, Nukina Nobuyuki, Furukawa Yoshiaki
Seibutsu Butsuri,
2013,The Biophysical Society of Japan General Incorporated Association
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Nishiura Yuko, Furukawa Yoshiaki
Seibutsu Butsuri,
2013,The Biophysical Society of Japan General Incorporated Association
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Wakahara Yuma, Honda Kazuki, Furukawa Yoshiaki
Seibutsu Butsuri,
2013,The Biophysical Society of Japan General Incorporated Association
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Nomura Takao, Furukawa Yoshiaki
Seibutsu Butsuri,
2013,The Biophysical Society of Japan General Incorporated Association
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Ogawa Mariko, Shidara Hisashi, Oka Kotaro, Furukawa Yoshiaki
Seibutsu Butsuri,
2013,The Biophysical Society of Japan General Incorporated Association
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2P030 Folding mechanism of bacterial SOD1 regulated by disulfide formation(01B. Protein: Structure & Function,Poster)
Sakurai Yasuyuki, Furukawa Yoshiaki
Seibutsu Butsuri,
2013,The Biophysical Society of Japan General Incorporated Association
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2B1534 Redox environment is an intracellular factor to operate distinct pathways for protein aggregation(Proteins:Structure & Function II:Theory, Aggregation,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)
Furukawa Yoshiaki
Seibutsu Butsuri,
2012,The Biophysical Society of Japan General Incorporated Association
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3C0900 Tandem-like fusion of two heterologous RNA-recognition motifs in TDP-43 enhances the specificity to its target nucleotide sequence(Nucleic Acids,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)
Suzuki Yo, Furukawa Yoshiaki
Seibutsu Butsuri,
2012,The Biophysical Society of Japan General Incorporated Association
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2B1610 Destabilization of SOD1 facilitates abnormal scrambling of its disulfide bond in the familial form of amyotrophic lateral sclerosis(Proteins:Structure & Function II:Theory, Aggregation,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)
Toichi Keisuke, Furukawa Yoshiaki
Seibutsu Butsuri,
2012,The Biophysical Society of Japan General Incorporated Association
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2B1558 A mechanism controlling the morphologies of protein aggregates by "post-aggregation oxidation"(Proteins:Structure & Function II:Theory, Aggregation,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)
Mitomi Yasushi, Nomura Takao, Kurosawa Masaru, Nukina Nobuyuki, Furukawa Yoshiaki
Seibutsu Butsuri,
2012,The Biophysical Society of Japan General Incorporated Association
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1D1348 P19 Morphological and biochemical properties of protein aggregates controlled by "post-aggregation modifications"(Protein: Property 1,The 49th Annual Meeting of the Biophysical Society of Japan)
Mitomi Yasushi, Furukawa Yoshiaki
Seibutsu Butsuri,
2011,The Biophysical Society of Japan General Incorporated Association
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1D1412 A thiol-disulfide status in SOD1 controls distinct pathways for aggregate formation in amyotrophic lateral sclerosis(Protein: Property 1,The 49th Annual Meeting of the Biophysical Society of Japan)
Toichi Keisuke, Furukawa Yoshiaki
Seibutsu Butsuri,
2011,The Biophysical Society of Japan General Incorporated Association
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2P048 1E1420 Structural polymorphism of protein aggregates and its pathological relevance(The 48th Annual Meeting of the Biophysical Society of Japan)
Furukawa Yoshiaki, Kaneko Kumi, Yamanaka Koji, Nukina Nobuyuki
Seibutsu Butsuri,
2010,The Biophysical Society of Japan General Incorporated Association
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1P-058 Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases(Protein:Property, The 47th Annual Meeting of the Biophysical Society of Japan)
Furukawa Yoshiaki, Kaneko Kumi, Kurosawa Masaru, Matsumoto Gen, Nukina Nobuyuki
Seibutsu Butsuri,
2009,The Biophysical Society of Japan General Incorporated Association
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2P-076 Molecular dissection of SOD1 aggregation and its structural rationale(The 46th Annual Meeting of the Biophysical Society of Japan)
Furukawa Yoshiaki, Kaneko Kumi, Nukina Nobuyuki
Seibutsu Butsuri,
2008,The Biophysical Society of Japan General Incorporated Association
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Furukawa Yoshiaki, Nukina Nobuyuki
Seibutsu Butsuri,
2006,The Biophysical Society of Japan General Incorporated Association