Terakawa, Mitsuhiro

写真a

Affiliation

Faculty of Science and Technology, Department of Electronics and Electrical Engineering （Yagami）

Position

Associate Professor

E-mail Address

E-mail address

Related Websites
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Career 【 Display / hide 】

  • 2005
    -
    2007

    Japan Society for the Promotion of Science, Doctoral Course Students (DC)

  • 2007
    -
    2008

    Massachusetts General Hospital, Wellman Center for Photomedicine, Research Fellow

  • 2007
    -
    2008

    Japan Society for the Promotion of Science, Postdoctoral Fellow

  • 2009
    -
    2010

    Keio University, Research Associate

  • 2010.04
    -
    2013.03

    Keio University, Department of Electronics and Electrical Engineering, Assistant Professor

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Academic Background 【 Display / hide 】

  • 2003.03

    Keio University, Science and Technology, Department of Electronics and Electrical Engineering

    University, Graduated

  • 2005.03

    Keio University, Science and Technology, Integrated Design Engineering

    Graduate School, Completed, Master's course

  • 2007.09

    Keio University, Science and Technology, Integrated Design Engineering

    Graduate School, Completed, Doctoral course

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Academic Degrees 【 Display / hide 】

  • 博士（工学）, 慶應義塾大学, 2007.09

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Matters concerning Career Achievements 【 Display / hide 】

  • 2013.04
    -
    2014.03

    電子工学科２年生担任

  • 2014.04
    -
    2015.03

    大学院総合デザイン工学専攻　専攻幹事

  • 2014.04
    -
    2015.03

    電子工学科３年生担任

  • 2016.04
    -
    2018.03

    大学院総合デザイン工学専攻　専攻幹事

  • 2016.10
    -
    2017.09

    理工学メディアセンター協議会委員

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Research Areas 【 Display / hide 】

  • Optical engineering, Photon science (laser processing, multi-photon manufacturing, softmaterials and biomaterials)

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Research Keywords 【 Display / hide 】

  • Laser processing

  • Soft materials

  • Biomaterials

  • Laser-based precise processing

  • Multi-photon photoreduction and photopolymerization

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Books 【 Display / hide 】

  • Micro and Nano Fabrication Technology

    Mitsuhiro Terakawa, Springer, 2018

    Scope: Chapter "Femtosecond Laser Direct Writing"

  • Ultrafast Laser Processing: From Micro- to Nanoscale

    Mitsuhiro Terakawa, Minoru Obara, Pan Stanford Publishing, 2013

    Scope: Chapter 7 Nanoablation Using Nanosphere and Nanotip

  • Gold Nanoparticles: Properties, Characterization, and Fabrication

    Y. Tanaka, M. Terakawa, M. Obara, N. Nedyalkov, P. Atanasov, Nova Science Publishers, 2009

    Scope: Chapter 6 Plasmonic Nanopatterning of the Material Surface Mediated with Gold Nanoparticles Excited by a Femtosecond Laser Pulse

  • 「ウイルスを用いない遺伝子導入法の材料, 技術, 方法論の新たな展開」

    佐藤俊一, 寺川光洋, 小原實, メディカルドゥ, 2006

    Scope: 160-166

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Papers 【 Display / hide 】

  • Femtosecond laser-induced graphitization of transparent cellulose nanofiber films

    Fumiya Morosawa, Shuichiro Hayashi, Mitsuhiro Terakawa

    ACS Sustainable Chemistry & Engineering 9 （ 7 ） 2955 - 2961 2021.02

    Research paper (scientific journal), Joint Work, Accepted

  • Fabrication of hollow channels surrounded by gold nanoparticles in hydrogel by femtosecond laser irradiation

    Izumi Takayama, Akito Katayama, Mitsuhiro Terakawa

    Nanomaterials （Nanomaterials)  10 （ 12 ） 2529 - 10 2020.12

    Research paper (scientific journal), Joint Work, Accepted

    　View Summary

    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The fabrication of hollow channels surrounded by gold nanoparticles in poly(ethylene glycol) diacrylate (PEGDA) is demonstrated. The absorption spectra show that gold nanoparticles were formed at the periphery of the focus by reduction of gold ions. The microscope observation and Raman spectroscopy analyses indicate that the center of the channels were void of PEGDA, which can be attributed to the femtosecond laser-induced degradation of the hydrogel. Since both the hydrogel and gold nanoparticles are biocompatible, this technique of fabricating hollow channels surrounded by gold nanoparticles is promising for tissue engineering, drug screening, and lab-on-a-chip devices.

  • Anionic fluorophore-assisted fabrication of gold microstructures inside a hydrogel by multi-photon photoreduction

    Manan Machida, Weilu Shen, Hiroaki Onoe, Yuki Hiruta, Alexander Heisterkamp, Eric Mazur, and Mitsuhiro Terakawa

    Optical Materials Express （The Optical Society (OSA))  11 （ 1 ） 48 - 58 2020.12

    Research paper (scientific journal), Joint Work, Accepted

    　View Summary

    © 2020 Optical Society of America. All Rights Reserved. The fabrication of accentuated gold microstructures is demonstrated by multi-photon photoreduction inside an anionic fluorophore-containing hydrogel. We attempted to facilitate gold-ion photoreduction near the focal point of laser pulses, expecting the donation of electrons by the oxidation of fluorophores in the vicinity of gold ions. The presence of anionic FITCdextran also inhibited the spontaneous reduction in untargeted zones, which is attributed to the coordination of gold ions and the anionic FITC-dextran. Simultaneous facilitation and inhibition are promising for the fabrication of dense metal microstructures in the targeted zone while maintaining the hydrogel's light permeability.

  • Femtosecond-laser-induced graphitic carbon from transparent cellulose nanofiber films

    Morosawa F., Hayashi S., Terakawa M.

    2020 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2020 - Proceedings （2020 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2020 - Proceedings)   2020.08

    ISSN  9780646825045

    　View Summary

    © 2020 IEEE. The fabrication of electrically conductive structures by femtosecond-laser irradiation of a cellulose nanofiber (CNF) film was demonstrated. Raman analyses indicated the formation of graphitic carbon, which is attributable to the electrical conductivity of the structures.

  • Multiphoton photoreduction for dual-wavelength-light-driven shrinkage and actuation in hydrogel

    Kosuke Mizuguchi, Yo Nagano, Hiroaki Nishiyama, Hiroaki Onoe, Mitsuhiro Terakawa

    Optical Materials Express （The Optical Society (OSA))  10 （ 8 ） 1931 - 1931 2020.07

    Research paper (scientific journal), Joint Work, Accepted

    　View Summary

    © 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. The dual-wavelength-driven shrinkage of metal microstructures and hydrogel actuation are demonstrated by the fabrication of multi-metal microstructures in hydrogels by multiphoton photoreduction. Silver and gold microstructures were fabricated in a poly-Nisopropylacrylamide (PNIPAm) hydrogel. Because of the different optical resonances of the metals, wavelength-dependent shrinkage of metal microstructures was demonstrated concurrently with the volume change of the supporting hydrogel by light stimulation. Furthermore, the direction of actuation of the hydrogel was controlled by switching the wavelength of light stimulation. The results indicate the potential of multiphoton photoreduction for applications in light-driven optical components and micro-robots fabricated with soft materials.

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Reviews, Commentaries, etc. 【 Display / hide 】

  • フェムト秒レーザー改質による高分子材料への導電性付与

    林秀一郎, 寺川光洋

    表面技術 71 ( 11 ) 684 - 688 2020.11

  • 超短パルスレーザーによる多光子還元

    寺川光洋

    光アライアンス 30 ( 8 ) 55 - 58 2019.08

    Introduction and explanation (commerce magazine), Single Work

  • Femtosecond Laser Processing of Biodegradable Polymers

    Mitsuhiro Terakawa

    Applied Sciences 8 ( 7 ) 1123 2018.07

    Introduction and explanation (scientific journal), Single Work

    　View Summary

    © 2018 by the authors. Biodegradable polymers have attracted increasing attention in tissue engineering and drug delivery systems owing to their high biocompatibility and biodegradability. Among the various methods for shape forming and modification of biodegradable polymers, laser processing has advantages in a dry processing approach that can process complex-shaped surfaces without using toxic chemical components. This review provides an overview of femtosecond laser processing of biodegradable polymers, especially in the last decade. The interaction mechanism of femtosecond laser pulse and biodegradable polymers, e.g., bond dissociation after laser irradiation, affects the degradable property of biodegradable polymers, which has the potential to control the degradation and sustainability of a structure. Applied studies on controlling cell behavior, tissue scaffolding, and drug release are also described.

  • フェムト秒レーザーによるソフトマテリアル・金属複合微細構造の作製

    寺川光洋、町田茉南、中島康貴

    レーザー研究 (レーザー学会)  46 ( 5 ) 272 - 276 2018.05

    Introduction and explanation (scientific journal), Joint Work

  • 短パルス光の音響的および機械的作用に基づいた薬剤輸送セラノスティックス

    角井泰之、川内聡子、寺川光洋、佐藤俊一

    レーザー研究 45 ( 11 ) 709 - 713 2017.11

    Introduction and explanation (scientific journal), Joint Work

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Presentations 【 Display / hide 】

  • (Invited) Femtosecond laser-induced modification of elastomers to conductive materials

    M. Terakawa, S. Hayashi, F. Morosawa, N. Nedyalkov

    The International School on Quantum Electronics "Laser Physics and Applications (ISCQE) (2020), 2020.09, Oral Presentation(guest/special)

  • (Invited) Multiphoton photoreduction in hydrogel

    M. Terakawa

    14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO Pacific Rim 2020), 2020.08, Oral Presentation(guest/special)

  • Femtosecond-laser-induced graphitic carbon from transparent cellulose nanofiber films

    F. Morosawa, S. Hayashi, and M. Terakawa

    14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO Pacific Rim 2020), 2020.08, Poster (general)

  • Fabrication of the light-responsive microchannel inside hydrogel

    Yo Nagano, Kosuke Mizuguchi, Hiroaki Onoe, Mitsuhiro Terakawa

    21st International Symposium on Laser Precision Microfabrication 2020 (LPM2020), 2020.06, Oral Presentation(general)

  • (Invited) Spatially-targeted laser fabrication of multimaterial microstructures in hydrogel

    M. Terakawa, M. Machida, K. Mizuguchi, R. Sano, H. Onoe, T. Niidome, A. Heisterkamp

    Photonics West 2020, 2020.02, Oral Presentation(guest/special)

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 回折限界を超える極微細金属構造のレーザーファブリケーション

    2018.07
    -
    2021.03

    文部科学省・日本学術振興会, 科学研究費補助金　挑戦的研究（萌芽）, Research grant, Principal Investigator

  • 三次元多光子レーザープロセシングによる機能因子放出スキャフォールドの実現

    2018.04
    -
    2022.03

    文部科学省・日本学術振興会, 科学研究費補助金　基盤研究(B), 寺川光洋, Research grant, Principal Investigator

  • レーザ直接描画法による３次元フレキシブル金属構造の作製

    2016.12
    -
    2019.03

    公益財団法人　天田財団, 重点研究開発助成Ｂ課題研究, No Setting, Principal Investigator

  • 多機能光学インプラントの開発

    2016.04
    -
    2018.03

    文部科学省・日本学術振興会, 二国間交流事業共同研究/セミナー, Commissioned ｒesearch, Principal Investigator

  • 超高速ミー散乱増強光の多光子過程による再生医療用薬剤放出技術の研究

    2014.04
    -
    2018.03

    Grant-in-Aid for Scientific Research, Research grant, Principal Investigator

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Intellectual Property Rights, etc. 【 Display / hide 】

  • レーザーにより透明材料表面もしくは内部に炭化ケイ素(SiC)を一括作製する方法

    Application No.： 特願2018-92489  2018.05 

  • レーザーを用いた薬剤放出方法

    Application No.： 2013-046732  2013.03 

    Patent, National application

  • 移植組織または臓器への薬剤導入方法ならびに薬剤導入装置

    Application No.： 特願2007-196580  2007.07 

    Announcement No.： 特開2008-49150   

    Patent, National application

  • Method and apparatus for drug delivery to tissue or organ for transplant

    Application No.：   2007 

    Announcement No.： US 2009/0233987 A1  2009 

    Patent, PCT international application

  • 細胞への薬剤導入方法および細胞への薬剤導入装置

    Application No.： 特願2006-113384  2006.04 

    Announcement No.： 特開2007-284379   

    Patent, National application

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Awards 【 Display / hide 】

  • 電子・情報・システム部門研究会 優秀論文発表賞

    2014.09, 電気学会

  • 応用物理学会　講演奨励賞

    TERAKAWA Mitsuhiro, 2012.03, 応用物理学会, フェムト秒レーザの多微粒子レンズ集光場による細胞膜の単一パルスプロセッシング

    Type of Award： Awards of National Conference, Council and Symposium

  • 慶應義塾大学 総合デザイン工学専攻 優秀研究活動賞 (博士)

    TERAKAWA Mitsuhiro, 2008.03

    Type of Award： Keio commendation etc.

  • 慶應義塾大学 藤原賞

    TERAKAWA Mitsuhiro, 2007.03

    Type of Award： Keio commendation etc.

  • 日本光学会年次学術講演会 第2回Optics and Photonics Japanベストプレゼンテーション賞

    TERAKAWA Mitsuhiro, 2006.11

    Type of Award： Awards of National Conference, Council and Symposium

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Other 【 Display / hide 】

  • 2017年11月

    　View Details

    The Optical Society (OSA) News Release: Metal-Silicone Microstructures Could Enable New Types of Flexible Optical and Electrical Devices

  • 2014年03月

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    SPIE Newsroom: Femtosecond laser pulses for smart drug delivery

  • 2012年04月

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    SPIE Newsroom: Ultrafast near- and far-field nanoablation patterning

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Courses Taught 【 Display / hide 】

  • RECITATION IN ELECTRONICS AND INFORMATION ENGINEERING

    2020

  • PHYSICS D

    2020

  • PHYSICS C

    2020

  • OPTICS AND QUANTUM ELECTRONICS

    2020

  • LASER PROCESSING

    2020

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Memberships in Academic Societies 【 Display / hide 】

  • SPIE, Senior Member, 

    2019.06
    -
    Present

  • OSA, Senior Member, 

    2019.06
    -
    Present

  • Japan Laser Processing Society, 

    2013.04
    -
    Present

  • Japan Society for Laser Surgery and Medicine, 

    2012.11
    -
    2020.09

  • The Japan Society of Applied Physics, 

    2011.06
    -
    Present

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Committee Experiences 【 Display / hide 】

  • 2020.04
    -
    Present

    委員（光加工・計測分科会）, 光産業技術振興協会　光技術動向調査委員会

  • 2020.04
    -
    Present

    光学編集委員, 日本光学会

  • 2020.04
    -
    Present

    Program Committee, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XXI , SPIE Photonics West 2021

  • 2020.04
    -
    Present

    Program Committee, Laser Applications in Microelectronic and Optoelectronic Manufacturing (LAMOM) XXVI, SPIE Photonics West 2021

  • 2020.04
    -
    Present

    Program Committee, Nano Track, ICALEO 2020 (39th International Congress on Applications of Lasers & Electro-Optics), LIA (The Laser Institute)

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