Uno, Shunsuke

写真a

Affiliation

School of Medicine, Department of Infectious Diseases (Shinanomachi)

Position

Instructor

 

Research Areas 【 Display / hide

  • Infectious disease medicine

Research Keywords 【 Display / hide

  • OPAT

  • Mycobacterium infection

  • Clinical Infectious Diseases

 

Books 【 Display / hide

  • Tuberculosis and Nontuberculous Mycobacterial Infections

    UNO Shunsuke, メディカルサイエンスインターナショナル, 2016.05

  • 臨床検査ガイド2015年改訂版

    UNO Shunsuke, 文光堂, 2015.03

  • 結核診療パーフェクトガイド

    UNO Shunsuke, 中外医学社, 2015.02

Papers 【 Display / hide

  • A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report

    Uno S., Horiuchi Y., Uchida T., Yonaha A., Miyata T., Nagano E., Kodama T., Hasegawa N.

    Journal of Infection and Chemotherapy (Journal of Infection and Chemotherapy)  24 ( 10 ) 849 - 851 2018.10

    ISSN  1341321X

     View Summary

    © 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases Aggregatibacter actinomycetemcomitans is well-known as the pathogen of gingivitis or periodontitis, and discitis or vertebral osteomyelitis cases caused by this organism have rarely been reported. Ampicillin or amoxicillin has been used in the previously reported discitis cases; however, no cases have been reported that is treated with levofloxacin. We report the first published case we chose levofloxacin to treat. We failed to perform the susceptibility testing because of the poor growth and fastidious nature of the organism, and the result of susceptibility of amoxicillin was unclear. Levofloxacin, which A. actinomycetemcomitans is usually susceptible to, can be an effective alternative oral antimicrobial agent in such cases.

  • Stability of benzylpenicillin potassium and ampicillin in an elastomeric infusion pump

    Nakamura T., Enoki Y., Uno S., Uwamino Y., Iketani O., Hasegawa N., Matsumoto K.

    Journal of Infection and Chemotherapy (Journal of Infection and Chemotherapy)  24 ( 10 ) 856 - 859 2018.10

    ISSN  1341321X

     View Summary

    © 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases Some infectious diseases, such as infective endocarditis, osteomyelitis, and abscesses, require treatment with long-term intravenous antimicrobial treatment. Therefore, the patient is required to stay in the hospital to receive therapy, which lowers their quality of life. Establishing an outpatient parenteral antimicrobial therapy (OPAT) by continuous infusion pump is desired in Japan to overcome these issues. However, the 24-h stability of antimicrobial agents dissolved in infusion solutions is unclear. Thus, we investigated the stability of antimicrobial agents in five different infusion solutions in a clinical setting. Benzylpenicillin potassium (PCG) and ampicillin (ABPC) were dissolved separately in five different infusion solutions and kept at 25 or 31.1 °C for 24 h. The residual ratios were determined by high-performance liquid chromatography (HPLC). Dissolved PCG in acetate ringer solution remained stable for 24 h at temperatures of 25 and 31.1 °C (101.7 ± 1.4% and 92.9 ± 1.3%, respectively). In addition, the PCG solution did not adsorb onto the elastomeric infusion pump after 24 h at 31.1 °C. PCG dissolved in acetate ringer solution was also stable for 10 days after being kept in an elastomeric infusion pump at 4 °C (99.7 ± 0.5%). ABPC was unstable in all of the tested infusion solutions and temperatures. Based on our results, PCG in acetate ringer solution can be used in OPAT with continuous infusion pumps.

  • Respiratory infectious diseases in patients with diabetes

    Uno S., Hasegawa N.

    Journal of the Japan Diabetes Society (Journal of the Japan Diabetes Society)  61 ( 10 ) 668 - 670 2018

    ISSN  0021437X

  • A case of diverticulitis with bacteremia caused by Raoultella ornithinolytica.

    UNO Shunsuke, HASE Ryota, HASHIMOTO Kohei, TOGUCHI Akihiro, OTSUKA Yoshihito, HOSOKAWA Naoto.

    日本臨床微生物学雑誌 2016 ( 26 ) 136 - 140 2016

    Research paper (scientific journal), Joint Work, Accepted

  • Acute Pyelonephritis and Candidemia Due to Candida lusitaniae: A Case Report

    UNO Shunsuke

    感染症学雑誌 2016 ( 90 ) 134 - 137 2016

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

Reviews, Commentaries, etc. 【 Display / hide

  • Antimicrobial Stewardship を意識した抗菌薬選択-発熱・頭痛を主訴に受診した65歳男性-

    UNO Shunsuke, KASAHARA Kei, HOSOKAWA Naoto, MIKAMO Hiroshige, YANO Harumi, AOKI Yosuke.

    日本化学療法学会雑誌 2015 ( 63 ) 494 - 498 2015

    Prompt report, short report, and research note, etc. (scientific journal), Joint Work

Research Projects of Competitive Funds, etc. 【 Display / hide

  • 複数回MAC感染マウスモデルによる、肺MAC症の病態解析および新規治療戦略開発

    2019.04
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 宇野 俊介, Grant-in-Aid for Early-Career Scientists , Principal Investigator

 

Courses Taught 【 Display / hide

  • SYMPTOMATOLOGY

    2021

  • INTRODUCTION TO CLINICAL CLERKSHIPS

    2021

  • INFECTIOUS DISEASES

    2021

  • ADVANCED HUMAN BODY AND PHYSIOLOGY

    2021

  • SYMPTOMATOLOGY

    2020

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Educational Activities and Special Notes 【 Display / hide

  • Tuberculosis and Nontuberculous Mycobacterial Infections

    2016.05

    , Development of Textbook and Teaching Material

  • 結核診療パーフェクトガイド

    2015.02

    , Development of Textbook and Teaching Material

 

Memberships in Academic Societies 【 Display / hide

  • The Japanese Society of Internal Medicine

     
  • The Japanese Association for Infectious DIseases

     
  • Japanese Society of Chemotherapy

     
  • The Japanese Society for Clinical Microbiology

     
  • The Japanese Society for Oriental Medicine