Fujioka, Masato

写真a

Affiliation

School of Medicine, Department of Otorhinolaryngology, Head and Neck Surgery (Shinanomachi)

Position

Assistant Professor/Senior Assistant Professor

External Links

Career 【 Display / hide

  • 2002.04
    -
    2003.03

    慶應義塾大学病院 研修医(耳鼻咽喉科)

  • 2003.04
    -
    2006.03

    慶應義塾大学医学部・医学研究科 博士課程(耳鼻咽喉科学)

  • 2006.04
    -
    2007.03

    慶應義塾大学医学部 生理学教室 特別研究助手

  • 2006.09
    -
    2009.09

    Senior Research fellow, Dpt of Otology and Laryngology, Harvard Medical School

  • 2007.04
    -
    2011.03

    慶應義塾大学医学部 耳鼻咽喉科学教室 助教

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Academic Background 【 Display / hide

  • 2002.03

    Keio University, Faculty of Medicine, 医学科

    University, Graduated

  • 2006.03

    Keio University, Graduate School, Division of Medicine, Otorhinolaryngology

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • MD, PhD, Keio University, Dissertation, 2006.03

Licenses and Qualifications 【 Display / hide

  • 医師免許, 2002

 

Research Areas 【 Display / hide

  • Laboratory animal science (Laboratory Animal Studies)

  • Molecular biology (Molecular Biology)

  • Immunology

  • Otorhinolaryngology (Otology, Audiology)

Research Keywords 【 Display / hide

  • MRI

  • iPSC based drug discovery

  • Meniere disease

  • inner ear regeneration

  • endoscopic ear surgery

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Research Themes 【 Display / hide

  • auditory network in the cortex, 

    2012
    -
    Present

  • Disease specific iPSCs for the drug discovery and development, 

    2012
    -
    Present

  • inner ear regeneration, 

    2004
    -
    Present

 

Papers 【 Display / hide

  • Proinflammatory Cytokines Expression in Noise-Induced Damaged Cochlea

    Fujioka Masato

    J. Neuroscience Res 83 ( 4 ) 575-583 2006.04

    Research paper (scientific journal), Single Work, Accepted

  • 下垂体腫瘍摘出術後に脳膿瘍を形成した蝶形骨洞篩骨洞嚢胞の1例

    Fujioka Masato

    耳鼻咽喉科・頭頸部外科 76 ( 12 ) 867-870 2004.11

    Research paper (scientific journal), Single Work, Accepted

  • 蝶形骨洞真菌症の2症例

    Fujioka Masato

    耳鼻咽喉科・頭頸部外科 75 ( 8 ) 566-570 2003.01

    Research paper (scientific journal), Joint Work, Accepted

  • Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss.

    Fujioka Masato Hosoya M, Sone T, Okamoto S, Akamatsu W, Ukai H, Ueda HR, Ogawa K, Matsunaga T, Okano H.

    Cell Rep. 18 ( 1 ) 68 - 81 2017.01

    Research paper (scientific journal), Accepted

  • Overlapping expression of anion exchangers in the cochlea of a non-human primate suggests functional compensation.

    Fujioka Masato Hosoya M, Fujioka M, Kobayashi R, Okano H, Ogawa K.

    Neurosci Res. 110   1 - 10 2016.09

    Research paper (scientific journal)

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Papers, etc., Registered in KOARA 【 Display / hide

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Presentations 【 Display / hide

  • An efficient screening method using inner-ear-derived spheres for selection of compounds that induce hair cell differentiation

    Hosoya, Makoto, Fujioka, Masato, Jeon, Sang-Jun, Okano, Hirotaka J., Edge, Albert, Okano, Hideyuki

    NEUROSCIENCE RESEARCH, 2008

  • A novel gamma-secretase inhibitor, LY411575, replaced auditory hair cells and recovered hearing loss after severe acoustic trauma in mice

    Fujioka, Masato, Hosoya, Makoto, Wakabayashi, Kenichiro, Jeon, Sang-Jun, Okano, Hirotaka James, Kanzaki, Sho, Ogawa, Kaoru, Edge, Albert, Okano, Hideyuki

    NEUROSCIENCE RESEARCH, 2008

  • The effect of anti-interleukin-6 receptor antibody in noise induced damaged cochlea

    Wakabayashi, Kenichiro, Fujioka, Masato, Kanzaki, Sho, Yamashita, Daisuke, Masuda, Masatsugu, Okano, James Hirotaka, Okano, Hideyuki, Ogawa, Kaoru

    NEUROSCIENCE RESEARCH, 2008

  • Analysis of inner ear-selective cis-regulatory enhancer of Sox21 gene

    Nakagawa, Fumiko, Fujioka, Masato, Hosoya, Makoto, Hayashi, Ken, Okano, Hirotaka J., Edge, Albert, Okano, Hideyuki

    NEUROSCIENCE RESEARCH, 2008

Research Projects of Competitive Funds, etc. 【 Display / hide

  • 多層オミックスとiPS技術,霊長類モデルを駆使した加齢性難聴への挑戦

    2019.06
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 藤岡 正人, Grant-in-Aid for Challenging Research (Pioneering), Principal Investigator

  • Development of novel therapeutics for the cochlear hearing impairments by using hiPSCs and common marmoset models

    2018.04
    -
    2021.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 藤岡 正人, Grant-in-Aid for Scientific Research (A) , Principal Investigator

  • Modeling inner ear cilliopathy using patient derived iPS cells

    2017.06
    -
    2019.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 藤岡 正人, Grant-in-Aid for Challenging Research (Exploratory) , Principal Investigator

  • In vitro "virtual biopsy" of cochlear cells by using Wolfram syndrome patients derived hiPSCs

    2015.04
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 藤岡 正人, Grant-in-Aid for Challenging Exploratory Research, Principal Investigator

  • ヒトiPS細胞と小型霊長類コモンマーモセットを用いた蝸牛有毛細胞再生の前臨床検討

    2015.04
    -
    2018.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 藤岡 正人, Grant-in-Aid for Scientific Research (B), Principal Investigator

Intellectual Property Rights, etc. 【 Display / hide

  • 音響外傷難聴モデル動物の作製用の音響暴露装置

    Application No.: 特願2017-181755  2017.09 

    Patent, Joint

  • 音響外傷難聴モデル動物の作製方法及びそれにより作製される音響外傷難聴モデル動物

    Application No.: 特願2017-181683  2017.09 

    Patent, Joint

  • 内耳性難聴治療薬

    Application No.: PCT/JP2016/050861  2016.01 

    Patent, Joint

  • 内耳細胞誘導方法

    Application No.: 特願2015-98423(P2015-98423)  2015.05 

    Announcement No.: 特開2015-231365(P2015-231365A)  2015.12 

    Patent, Joint

  • Treating Hearing Loss

    Application No.: PCT/US2013/058446  2013.09 

    Announcement No.: WO2014039781 A1  2014.03 

    Patent, Joint

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Awards 【 Display / hide

  • 14th. Harold F. Schuknecht Travel Award

    2016.06

  • 第14回Harold F. Schuknecht Travel Award

    2014, シュクネヒトソサイエティ

  • Young Investigator Award, Keio University School of Medicine Alumni Association (Sanshikai)

    2012.11

  • International Society of Stem Cell Research Travel Award

    2012.06

  • 三四会奨励賞

    2012

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Courses Taught 【 Display / hide

  • PATHOPHYSIOLOGICAL ISSUES IN CHRONIC CARE

    2019

  • LECTURE SERIES, OTORHINOLARYNGOLOGY

    2019

Courses Previously Taught 【 Display / hide

  • 慶應義塾大学医学部 学生講義「耳科学総論」

    Keio University, 2017

  • 慶應義塾大学耳鼻咽喉科 専修医クルズス「中耳換気生理/内視鏡下耳科手術」

    Keio University, 2017

  • 慶應義塾大学大学院医学研究科修士課程 実技指導

    Keio University, 2017

  • 慶應義塾大学医学部耳鼻咽喉科 学位(博士:乙)指導

    Keio University, 2016

  • 慶應義塾大学大学院医学研究科修士課程 実技指導

    Keio University, 2016

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Memberships in Academic Societies 【 Display / hide

  • 日本耳鼻咽喉科学会

     
  • 日本耳科学会

     
  • 日本聴覚医学会

     
  • 日本めまい平衡医学会

     
  • 日本再生医療学会

     

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Committee Experiences 【 Display / hide

  • 2016
    -
    Present

    薬事委員, 慶應義塾大学病院

  • 2016
    -
    Present

    クリニカルアナトミー委員, 慶應義塾大学医学部

  • 2016
    -
    Present

    生命倫理監視委員会, 慶應義塾大学医学部

  • 2016
    -
    Present

    選挙管理委員会, 日本聴覚医学会