Kanzaki, Sho

写真a

Affiliation

School of Medicine, Department of Otorhinolaryngology, Head and Neck Surgery (Shinanomachi)

Position

Assistant Professor/Senior Assistant Professor

External Links

Academic Degrees 【 Display / hide

  • 遺伝性難聴モデルマウスに対する遺伝子導入の検討, Keio University, Coursework, 2002.03

 

Research Areas 【 Display / hide

  • Otorhinolaryngology

Research Keywords 【 Display / hide

  • アレルギー学

  • 神経耳科学

  • 耳科学

  • 顔面神経

Research Themes 【 Display / hide

  • bone resorption of ossicles, 

    2007
    -
    2009

 

Books 【 Display / hide

  • Degeneration and regeneration in neuron

    Kanzaki S., Kerala, Inidia Research Signpost, 2006.01

    Scope: 37-52

  • Hearing impairment

    Kanzaki J, Kanzaki S., 2004

    Scope: 282-286

Papers 【 Display / hide

  • Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear

    Sato, Mitsuo P., Higuchi, Taiga, Nin, Fumiaki, Ogata, Genki, Sawamura, Seishiro, Yoshida, Takamasa, Ota, Takeru, Hori, Karin, Komune, Shizuo, Uetsuka, Satoru, Choi, Samuel, Masuda, Masatsugu, Watabe, Takahisa, Kanzaki, Sho, Ogawa, Kaoru, Inohara, Hidenori, Sakamoto, Shuichi, Takebayashi, Hirohide, Doi, Katsumi, Tanaka, Kenji F., Hibino, Hiroshi

    FRONTIERS IN MOLECULAR NEUROSCIENCE 10   95 - 100 2017.09

    Research paper (scientific journal),  ISSN  1662-5099

  • Clinical characteristics of patients with tinnitus evaluated with the Tinnitus Sample Case History Questionnaire in Japan

    Kojima Takashi, Kanzaki Sho, Oishi Naoki, Ogawa Kaoru

    PLoS ONE 12 ( 8 )  2017.08

    ISSN  1932-6203

     View Summary

    <p>Background: The Tinnitus Sample Case History Questionnaire was determined as a standardized questionnaire for obtaining patient case histories and for characterizing patients into subgroups at the Tinnitus Research Initiative in 2006. In this study, we developed a Japanese version of this questionnaire for evaluating the clinical characteristics of patients with tinnitus. The Japanese version of the questionnaire will be available for evaluating treatments for tinnitus and for comparing data on tinnitus in research centers. Aims/Objectives: To evaluate the clinical characteristics of patients with tinnitus in Japan using a newly developed Japanese version of Tinnitus Sample Case History Questionnaire. Study design: This was a prospective study based on patient records. Setting: University hospitals, general hospitals, and clinics. Subjects and methods: We collected patient data using a Japanese translated version of the Tinnitus Sample Case History Questionnaire. In total, 584 patients who visited our institutions in Japan between August 2012 and March 2014 were included (280 males and 304 females; age 13–92 years; mean age, 60.8). We examined patients after dividing them into two groups according to the presence or absence of hyperacusis. The collected results were compared with those from the Tinnitus Research Initiative database. Results: Compared with the TRI database, there were significantly more elderly female patients and fewer patients with trauma-associated tinnitus. There was a statistically lower ratio of patients with hyperacusis. We found that patients with tinnitus in addition to hyperacusis had greater tinnitus severity and exhibited higher rates of various complications. Conclusion: The Japanese version of the Tinnitus Sample Case History Questionnaire developed in this study can be a useful tool for evaluating patients with tinnitus in Japan. The results of this multicenter study reflect the characteristics of patients with tinnitus who require medical care in Japan. Our data provides a preliminary basis for an international comparison of tinnitus epidemiology.</p>

  • Round Window Application of an Active Middle Ear Implant: A Comparison With Hearing Aid Usage in Japan

    Iwasaki, Satoshi, Usami, Shin-ichi, Takahashi, Haruo, Kanda, Yukihiko, Tono, Tetsuya, Doi, Katsumi, Kumakawa, Kozo, Gyo, Kiyofumi, Naito, Yasushi, Kanzaki, Sho, Yamanaka, Noboru, Kaga, Kimitaka

    OTOLOGY & NEUROTOLOGY 38 ( 6 ) E145 - E151 2017.07

    Research paper (scientific journal),  ISSN  1531-7129

  • Assessment of hyperacusis with a newly produced Japanese version of the Khalfa hyperacusis questionnaire

    Oishi Naoki, Yamada Hiroyuki, Kanzaki Sho, Kurita Akihiro, Takiguchi Yoichiro, Yuge Isamu, Asama Yoji, Masuda Masatsugu, Ogawa Kaoru

    Acta Oto-Laryngologica    1 - 5 2017.04

    ISSN  0001-6489

     View Summary

    <p>Objectives: The purpose of this study was to determine the validity and reliability of a Japanese version of the Khalfa hyperacusis questionnaire (KHQ) and proposed a threshold KHQ score for classifying hyperacusis. Methods: In total, 112 patients with hyperacusis (group A) and 103 patients without hyperacusis (group B). The patients in group A were further classified into the following subgroups: subjects with hyperacusis as their chief complaint (n = 26, group A1) and subjects with hyperacusis accompanied by chief complaints of tinnitus and/or hearing loss (n = 86, group A2). Results: The average total questionnaire score for patients in group A was 11.8 ± 9.7, which was statistically significantly higher than that of patients in group B, 5.7 ± 4.8. Cronbach’s coefficients for internal consistency were high for the total score (0.92). The average total scores for groups A1 and A2 were 18.1 ± 11.1 and 9.9 ± 8.4, respectively, and the difference between the groups was statistically significant. Conclusions: We developed a Japanese version of the KHQ. It showed high reliability and validity; suggesting its usefulness in clinical practice. We propose that a total KHQ score of 16 is an appropriate cutoff for classifying hyperacusis</p>

  • Idiopathic sudden sensorineural hearing loss and acute low-tone sensorineural hearing loss

    Yoshida Tadao, Sone Michihiko, Kitoh Ryosuke, Nishio Shin Ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin Ichi

    Acta Oto-Laryngologica 137   S38 - S43 2017.03

    ISSN  0001-6489

     View Summary

    <p>Objectives: The aim of this study was to investigate the differences between idiopathic sudden sensorineural hearing loss (SSNHL), and acute low-tone sensorineural hearing loss (ALHL) using the results of a nationwide survey database in Japan and to analyze the variables associated with their clinical features and the severity of hearing impairment, treatment, and prognosis. Methods: Participants were patients registered between April 2014 and March 2016 in a multicenter epidemiological survey database involving 30 university hospitals and medical centers across Japan. Statistical analysis was performed to clarify the factors associated with their clinical characteristics and the severity of hearing impairment, treatment, and prognosis. Results: Idiopathic SSNHL and ALHL differed significantly in terms of male-to-female ratio, age distribution, and time from onset to start of treatment. The treatment methods and hearing prognosis also differed markedly between the two diseases. A majority (92%) of idiopathic SSNHL patients were administered some type of corticosteroid, while half of the ALHL patients received corticosteroids and a diuretic agent. Conclusion: The results suggested that idiopathic SSNHL and ALHL belonged to different categories of inner ear disease.</p>

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Papers, etc., Registered in KOARA 【 Display / hide

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Presentations 【 Display / hide

  • 両側難聴,顔面神経麻痺,めまいをきたした慢性肥厚性硬膜炎の一例

    Watabe takahisa, Kanzaki shou, Masuda masatsugu, Takiguhi youichirou, Inoue yasuhiro, Satou minako, Ogawa kaoru

    第155回日本耳鼻咽喉科学会東京地方部会, 2003.03, Oral Presentation(general)

  • Sendai virus vector gene transfer mediated middle and inner ear

    Kanzaki Sho, Shiotani Akihiro, Fukumura Masahiro, Hasegawa Mamoru, Ogawa Kaoru

    Association for Research in Otolaryngology, 2003.02, Poster (general)

  • 内耳の遺伝子治療

    Kanzaki shou

    第4回慶應義塾大学学術講演会, 2002.12, Oral Presentation(general)

  • 聴神経腫瘍症例における耳音響放射所見

    Inoue Yasuhiro, Ogawa Kaoru, Kanzaki Shou, Ide Rika, Takiguchi Youichirou, Kanzaki Jin

    第47回日本聴覚医学会, 2002.10, Oral Presentation(general)

  • p27ノックアウトマウスにおける聴力閾値の検討

    Kanzaki shou, Inoue yasuhiro, Ogawa kaoru, Yoashu Rafaero

    第47回聴覚医学会, 2002.10, Oral Presentation(general)

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • analysis of osteoclasts involved in hearing loss and balance disorder

    2019.04
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 神崎 晶, Grant-in-Aid for Scientific Research (C), Principal Investigator

  • 内耳ドラッグ・デリバリー・システムの解析

    2015.04
    -
    2019.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 神崎 晶, Grant-in-Aid for Scientific Research (C), Principal Investigator

Awards 【 Display / hide

  • 平成26年度日本医師会医学研究奨励賞 

    神崎晶, 2017.11, 日本医師会, 「内耳再生医療をめざした内耳薬物動態の解明¬ 」

  • 1st Global Otology Research Forum (GLORF) Award

    Sho Kanzaki, 2013.11, Novel in vivo imaging analysis of an inner ear (spiral ganglion) drug delivery system in mice"(新しいイメージ解析によるマウス内耳薬物投与に関する検討)

  • Poster award of the 2010 Annual Meeting American Academy of Otolaryngology – Head and Neck Surgery & OTO Expo in Boston, MA ,USA  Hayashi K, Kanzaki S含む4名 The molecular mechanism of autophagy in auditory cells, poster presentation

    Hayashi K, Kanzaki S含む4名, 2010, AAO HNS, The molecular mechanism of autophagy in auditory cells

  • Poster award of the 2010 Annual Meeting American Academy of Otolaryngology – Head and Neck Surgery & OTO Expo in Boston, MA ,USA  Hayashi K, Kanzaki S含む4名 The molecular mechanism of autophagy in auditory cells, poster presentation

    Hayashi K, Kanzaki S含む4名, 2010, AAO HNS, The molecular mechanism of autophagy in auditory cells

  • 慶應義塾大学医学部三四会奨励賞受賞(平成16年度)

    2010, 慶應義塾大学医学部三四会, らせん神経説細胞の増殖

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Courses Taught 【 Display / hide

  • LECTURE SERIES, OTORHINOLARYNGOLOGY

    2020

  • INTRODUCTION TO CLINICAL CLERKSHIPS

    2020

  • DISEASES AND PHARMACOTHERAPY 3 (PSYCHIATRIC DISEASES AND OTHERS)

    2020

  • CLINICAL TRAINING IN DIAGNOSIS

    2020

  • CLINICAL TRAINING IN DIAGNOSIS

    2019

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Courses Previously Taught 【 Display / hide

  • 感覚器学(耳科学)

    慶應義塾大学医学部, 2018

  • 耳鼻咽喉科学

    慶應義塾大学看護学部, 2018

  • 耳鼻咽喉科学(薬学部)

    Keio University, 2017, Major subject, Lecture, Within own faculty, 100people

  • アレルギー学

    Keio University, 2017, Major subject, Lecture

Educational Activities and Special Notes 【 Display / hide

  • cadavar dissection course

    2014.12
    -
    Present

    , Special Affairs

     View Details

    instructor

  • 第44回日本医学教育学会 医学教育における新たなる武器 卒前・卒後医学教育における超高精細3D画像のコミュニケーションツールとしての有用性 特別セッション

    2012.07
    -
    Present

    , Lecture at Education Method and Practice

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    今西宣晶、当麻、高沖、相磯、佐藤幸男、堀口、神崎

  • 第44回日本医学教育学会

    2012.07
    -
    Present

    , Lecture at Education Method and Practice

     View Details

    神崎晶 相磯貞和、高沖英二、平形直人
    3次元動画,3次元画像による側頭 骨臨床解剖教育の効果について

  • 日本聴覚医学会講習会

    2010
    -
    Present

    , Special Affairs

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    聴覚検査の講義・実習の講師 講習会の事務

  • OSCE委員

    2010
    -
    Present

    , Special Affairs

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Memberships in Academic Societies 【 Display / hide

  • 日本聴覚医学会

     
  • 日本耳科学会

     
  • 日本耳鼻咽喉科学会

     
  • 日本アレルギー学会

     
  • 日本頭頚部外科学会

     

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Committee Experiences 【 Display / hide

  • 2017
    -
    Present

    片側性~非対称性難聴に対する人工聴覚器成績評価法検討ワーキンググループ委員(副委員長), 日本耳科学会

  • 2017
    -
    Present

    ガイドライン委員会委員, 日本聴覚医学会

  • 2016.10
    -
    Present

    トランスレーショナル委員会委員(委員長), 日本耳科学会

  • 2014.10
    -
    2016.09

    学会編集委員会委員(副委員長), 日本耳科学会

  • 2010
    -
    Present

    講習会委員, 日本聴覚医学会