研究者詳細 - 根岸　一乃

論文 - 根岸　一乃

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Effect of chromatic aberration on contrast sensitivity in pseudophakic eyes

Negishi, K., Ohnuma, K., Hirayama, N. and Noda, T.

Arch Ophthalmol 119 （ 8 ） 1154 - 8 2001年08月

ISSN 0003-9950

OBJECTIVE: To evaluate the effect of chromatic aberrations in pseudophakic eyes with various types of intraocular lenses (IOLs). PATIENTS AND METHODS: The study included 51 eyes of 33 patients who underwent cataract surgery. The eyes were divided into 3 groups according to the material from which their IOL was made: group 1, polymethyl methacrylate; group 2, silicone; and group 3, an acrylate/methacrylate copolymer. Ten normal phakic control eyes (group 4) underwent the same examination. Best-corrected distance visual acuity and contrast sensitivity were measured under white light and monochromatic light with wavelengths of 470 nm, 549 nm, and 630 nm, with the best correction under white light. RESULTS: There were no significant differences in best-corrected visual acuity and contrast sensitivity under the 549-nm monochromatic light in any group. However, under both white multichromatic light and 470- and 630-nm monochromatic light, the mean contrast sensitivity in group 3 tended to be lower, sometimes significantly, than in the other IOL groups. CONCLUSIONS: Our results showed that longitudinal chromatic aberrations of some IOLs may degrade the quality of the retinal image. Attention must be paid to the detailed optical performance of IOL materials to achieve good visual function.

Effect of chromatic aberration on ontrast sensitivity in pseudophakic eyes

Negishi Kazuno, Ohnuma Kazuhiko, Hirayama Norio, Noda Toru

Archives of Ophthalmology 119 （ 8 ） 1154-1158 2001年08月

研究論文（学術雑誌）, 共著

含水ゲル眼内レンズ挿入眼の術後早期コントラスト感度

阿部聡，平井香織，黒川直行，野田航介，細田ひろみ，林康司，小西美奈子，田中靖彦，根岸一乃

臨床眼科（医学書院） 55 （ 4 ） 565-567 2001年04月

研究論文（学術雑誌）, 共著

Effect of chromatic aberration on contrast sensitivity in pseudophakic eyes

Negishi K., Ohnuma K., Hirayama N., Noda T.

Archives of Ophthalmology 119 （ 8 ） 1154 - 1158 2001年

ISSN 0003-9950

Objective: To evaluate the effect of chromatic aberrations in pseudophakic eyes with various types of intraocular lenses (IOLs). Patients and Methods: The study included 51 eyes of 33 patients who underwent cataract surgery. The eyes were divided into 3 groups according to the material from which their IOL was made: group 1, polymethyl methacrylate; group 2, silicone; and group 3, an acrylate/methacrylate copolymer. Ten normal phakic control eyes (group 4) underwent the same examination. Best-corrected distance visual acuity and contrast sensitivity were measured under white light and monochromatic light with wavelengths of 470 nm, 549 nm, and 630 nm, with the best correction under white light. Results: There were no significant differences in best-corrected visual acuity and contrast sensitivity under the 549-nm monochromatic light in any group. However, under both white multichromatic light and 470- and 630-nm monochromatic light, the mean contrast sensitivity in group 3 tended to be lower, sometimes significantly, than in the other IOL groups. Conclusions: Our results showed that longitudinal chromatic aberrations of some IOLs may degrade the quality of the retinal image. Attention must be paid to the detailed optical performance of IOL materials to achieve good visual function.

患者選択はどのように行うのですか？

根岸一乃

あたらしい眼科 18 （臨増） 15-18 2001年

研究論文（学術雑誌）, 単著

Outcome of intraocular lens implantation in children

Nishiyama T., Kurosaka D., Nakamura K., Negishi K., Kato K.

Japanese Journal of Clinical Ophthalmology 54 （ 4 ） 525 - 529 2000年

ISSN 0370-5579

We performed intraocular lens (IOL) implantation in 6 eyes of 5 children using a new procedure. The ages ranged from 4 years 8 month to 8 years 10 months, average 6 years 1 month. The follow-up period ranged from 6 months to 3 years 9 months, average 17.5 months. Following circular capsulorhexis and aspiration of lens material, anterior vitrectomy and posterior capsulorhexis were performed. The optics of IOL fixated in the bag was then luxated posteriorly to create optic capture. There were no serious complications either intra- or postoperatively. Aftercataract was slight in degree and did not affect the visual acuity. All the eyes increased visual acuity by 2 lines or more. The endothelial cell loss averaged 2.9%. The postoperative myopic shift averaged 0.69 diopters. The present surgical modality promises to be safe and effective in treating cataract or posterior lenticonus in children after the axial length has stabilized after 2 years 6 months of age.

小児に対する眼内レンズ挿入術後の術後成績

西山隆恒、黒坂大次郎、中村邦彦、根岸一乃、加藤克彦

臨床眼科（医学書院） 54 525 - 529 2000年

研究論文（学術雑誌）, 共著

Various phenotypic expressions of familial aniridia with a PAX6 mutation [6]

Negishi K., Azuma N., Yamada M.

British Journal of Ophthalmology 83 （ 8 ） 991 - 992 1999年

ISSN 0007-1161

点眼麻酔白内障手術における鎮静剤（ジアゼパム）内服の必要性

江下忠彦、根岸一乃、蔵石さつき

あたらしい眼科（メディカル葵出版） 15 1587 - 1591 1998年

研究論文（学術雑誌）, 共著

5ゾーン屈折型多焦点眼内レンズ移植眼の術後視機能

根岸一乃

慶應医学 75 （ 1 ） T49 - T61 1998年

学位論文（博士）, 単著

Elschnig pearl formation along the posterior capsulotomy margin after neodymium:YAG capsulotomy

Kato, K., Kurosaka, D., Bissen-Miyajima, H., Negishi, K., Hara, E. and Nagamoto, T.

J Cataract Refract Surg 23 （ 10 ） 1556 - 60 1997年12月

ISSN 0886-3350

PURPOSE: To determine the incidence of Elschnig pearl formation along the capsulotomy margin (string of pearls) after neodymium:YAG (Nd:YAG) laser posterior capsulotomy and to elucidate its clinical features, predisposing factors, effect on visual function, and association with additional capsulotomy. SETTING: Keio University Hospital, Tokyo, Japan. METHODS: The records of 418 eyes that had had Nd:YAG posterior capsulotomy after cataract surgery were retrospectively reviewed. Of those, 315 were excluded for short follow-up (fewer than 12 months) or insufficient clinical examination data. In the remaining 103 eyes, the incidence of string of pearls was calculated, and its clinical features, predisposing factors, effect on visual function, and correlation with additional capsulotomy were evaluated. RESULTS: String of pearls was identified in 49 eyes (47.6%); 37 (75.5%) developed pearls within 1 year after Nd:YAG capsulotomy. The incidence was significantly higher in patients having intraocular lens implantation and continuous curvilinear capsulorhexis (CCC) than in those without (95.9 versus 61.1% and 97.9 versus 55.6%, respectively). No significant differences were found in patient age and sex, total Nd:YAG energy, and the presence of diabetes mellitus or high myopia. String of pearls caused visual disturbances in 17 eyes (34.7%). The rate of repeat capsulotomy was higher in patients with string of pearls than in those without (36.7 and 9.3%, respectively). CONCLUSIONS: String of pearls formation was a common and significant complication after Nd:YAG posterior capsulotomy. Intraocular lens implantation and CCC may promote its formation.

多目的眼内レンズの支持部強度

根岸一乃，蔵石さつき，松崎忠幸

臨眼 51 （ 13 ） 1909-1912 1997年12月

研究論文（学術雑誌）, 共著

Elschnig pearl formation along the posterior capsulotomy margin after neodymium : YAG Capsulotomy

Kato Katsuhiko, Kurosaka Daijiro, Miyajima-Bissen Hiroko, Negishi Kazuno, Hara Emiko, Nagamoto Toshiyuki

J Catoract Refract Surg 23 （ 10 ） 1556-1560 1997年12月

研究論文（学術雑誌）, 共著

Evaluation of a zonal-progressive multifocal intraocular lens

Negishi, K., Bissen-Miyajima, H., Kato, K., Kurosaka, D. and Nagamoto, T.

Am J Ophthalmol 124 （ 3 ） 321 - 30 1997年09月

ISSN 0002-9394

PURPOSE: To determine the clinical usefulness of a five-zone refractive multifocal intraocular lens. METHODS: After more than 1 year of follow-up, we evaluated the visual function of 22 patients (36 eyes) who had received the MPC-25NB intraocular lens for distance and near visual acuity, kinetic visual acuity, and near contrast sensitivity, and for patient satisfaction. RESULTS: Of 31 study eyes with less than 1.5 diopters of preoperative keratometric astigmatism, 28 (90.3%) achieved an uncorrected distance visual acuity of 20/40 or better; best-corrected distance visual acuity was 20/20 or better in 31 (86.1%) of 36 eyes. Near visual acuity with distance correction was 20/40 or better in 20 (60.6%) of 33 eyes. Kinetic visual acuity in these patients was comparable to that in patients with monofocal intraocular lenses. Distance visual acuity and near contrast sensitivity were below normal or within the low normal range. There was no significant difference in contrast visual acuity measured by variable contrast visual acuity charts between MPC-25NB and monofocal intraocular lens-implanted eyes (P > .05). Four (22.2%) of 18 patients did not require spectacles when the intraocular lens was implanted for emmetropia. Despite some complaints about near or night vision, all patients expressed satisfaction. CONCLUSIONS: The MPC-25NB lens provides a level of distance vision comparable to that of a monofocal intraocular lens and a useful level of near visual acuity without spectacles. However, we should carefully evaluate the indication for use of MPC-25NB in patients who require good near vision or night vision.

毛様溝縫着術中に破損したdimple付き眼内レンズの1例

松崎忠幸，根岸一乃，林康司，野田徹

眼科（金原出版） 39 （ 9 ） 1113-1117 1997年09月

研究論文（学術雑誌）, 共著

自己閉鎖創白内障術後早期のコントラスト視力と不正乱視

根岸一乃，ビッセン宮島弘子，富所敦男，大鹿哲郎，松崎忠幸，林康司

臨眼 50 （ 6 ） 1133-1136 1997年06月

研究論文（学術雑誌）, 共著

白内障手術--術後炎症--

根岸一乃

眼科手術 10 （ 1 ） 5-13 1997年01月

研究論文（学術雑誌）, 単著

Evaluation of a zonal-progressive multifocal intraocular lens

Negishi K., Bissen-Miyajima H., Kato K., Kurosaka D., Nagamoto T.

American Journal of Ophthalmology 124 （ 3 ） 321 - 330 1997年

ISSN 0002-9394

PURPOSE: To determine the clinical usefulness of a five-zone refractive multifocal intraocular lens. METHODS: After more than 1 year of follow-up, we evaluated the visual function of 22 patients (36 eyes) who had received the MPC 25NB intraocular tens for distance and near visual acuity, kinetic visual acuity, and near contrast sensitivity, and for patient satisfaction. RESULTS: Of 31 study eyes with less than 1.5 diopters of preoperative keratometric astigmatism, 28 (90.3%) achieved an uncorrected distance visual acuity of 20/40 or better; best-corrected distance visual acuity was 20/20 or better in 31 (86.1%) of 36 eyes. Near visual acuity with distance correction was 20/40 or better in 20 (60.6%) of 33 eyes. Kinetic visual acuity in these patients was comparable to that in patients with monofocal intraocular lenses. Distance visual acuity and near contrast sensitivity were below normal or within the low normal range. There was no significant difference in contrast visual acuity measured by variable contrast visual acuity charts between MPC- 25NB and monofocal intraocular lens-implanted eyes (P > .05). Four (22.2%) of 18 patients did not require spectacles when the intraocular lens was implanted for emmetropia. Despite some complaints about near or night vision, all patients expressed satisfaction. CONCLUSIONS: The MPC-25NB lens provides a level of distance vision comparable to that of a monofocal intraocular lens and a useful level of near visual acuity without spectacles. However, we should carefully evaluate the indication for use of MPC-25NB in patients who require good near vision or night vision.

Elschnig pearl formation along the posterior capsulotomy margin after neodymium

Kato K., Kurosaka D., Bissen-Miyajima H., Negishi K., Hara E., Nagamoto T.

Journal of Cataract and Refractive Surgery 23 （ 10 ） 1556 - 1560 1997年

ISSN 0886-3350

Purpose: To determine the incidence of Elschnig pearl formation along the capsulotomy margin (string of pearls) after neodymium:YAG (Nd:YAG) laser posterior capsulotomy and to elucidate its clinical features, predisposing factors, effect on visual function, and association with additional capsulotomy. Setting: Keio University Hospital, Tokyo, Japan. Methods: The records of 418 eyes that had Nd:YAG posterior capsulotomy after cataract surgery were retrospectively reviewed. Of those, 315 were excluded for short follow-up (fewer than 12 months) or insufficient clinical examination data. In the remaining 103 eyes, the incidence of string of pearls was calculated, and its clinical features, predisposing factors, effect on visual function, and correlation with additional capsulotomy were evaluated. Results: String of pearls was identified in 49 eyes (47.6%); 37 (75.5%) developed pearls within 1 year after Nd:YAG capsulotomy. The incidence was significantly higher in patients having intraocular lens implantation and continuous curvilinear capsulorhexis (CCC) than in those without (95.9 versus 61.1% and 97.9 versus 55.6%, respectively). No significant differences were found in patient age and sex, total Nd:YAG energy, and the presence of diabetes mellitus or high myopia. String of pearls caused visual disturbances in 17 eyes (34.7%). The rate of repeat capsulotomy was higher in patients with string of pearls than in those without (36.7 and 9.3%, respectively). Conclusions: String of pearls formation was a common and significant complication after Nd:YAG posterior capsulotomy. Intraocular lens implantation and CCC may promote its formation.

Strength of haptics of multipurpose intraocular lens

Negishi K., Kuraishi S., Matsuzaki T.

Japanese Journal of Clinical Ophthalmology 51 （ 13 ） 1909 - 1912 1997年

ISSN 0370-5579

We measured the strength of haptics of two types of intraocular lens (IOL) made by Nidek Co. One has equal haptics in diameter (NR-84C) and the other unequal ones (NR-84K). We used a digital force guage to which the optics of each IOL was fixed. The end of haptics was pulled either parallel or vertical to the optics at the speed of 40 mm/min. We recorded the strength of the force at the break point of the haptics. When the power was applied parallel to the optics, the breaking power was significantly less for NR-84K than NR-84C (p < 0.05). The haptics broke at their end for either type of IOL. When the power was applied vertical to the optics, the breaking power was the same for both types of IOL. The haptics broke at the end of haptics for NR-84K and near the root for NR-84C. The findings show that haptics unequal in diameter are weaker than those with equal ones. Standardization in the strength of haptics is desired in order to avoid their break during transscleral fixation of IOL.

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