Banno, Koji

写真a

Affiliation

School of Medicine, Department of Obstetrics and Gynecology (Gynecology) (Shinanomachi)

Position

Associate Professor

E-mail Address

E-mail address

External Links

Career 【 Display / hide

  • 1992.05
    -
    Present

    慶應義塾大学病院研修医

  • 1995.07
    -
    Present

    慶應義塾大学助手(医学部産婦人科学)

  • 1996.04
    -
    2000.03

    癌研究会癌研究所細胞生物部研究生

  • 2001.06
    -
    Present

    慶應義塾大学助手(医学部産婦人科学)

  • 2005.04
    -
    Present

    慶應義塾大学助手(医学部産婦人科学・外来医長)

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Academic Background 【 Display / hide

  • 1992

    Keio University, Faculty of Medicine

    University, Graduated

  • 2000

    Keio University, Graduate School, Division of Medicine, 婦人科腫瘍学・細胞生物学

    Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide

  • 博士(医学), Keio University, Coursework

Licenses and Qualifications 【 Display / hide

  • 日本臨床細胞学会 指導医

  • 日本婦人科腫瘍学会 専門医

  • がん治療暫定教育医

  • がん治療認定医

  • 日本婦人科腫瘍学会指導医

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Research Areas 【 Display / hide

  • Human genetics

  • Obstetrics and gynecology

Research Keywords 【 Display / hide

  • エピジェネテイクス

  • 子宮体癌

  • 子宮内膜

  • 子宮移植

  • 家族性腫瘍

 

Books 【 Display / hide

  • Nonhuman Primate Research in Uterus Transplantation.

    Kisu I, Banno K, Matoba Y, Aoki D. , Splinger, 2020.01

    Scope: Nonhuman Primate Research in Uterus Transplantation.,  Contact page: 57-67

  • Cell Biology of the Ovary, Stem Cells, Development, Cancer, and Clinical Aspects

    Kobayashi Y, Nomura H, Kataoka F, Tominaga E, Banno K, Aoki D, USA: Springer, 2018.05

    Scope: Clinical Management of Epithelial Ovarian Cancer.

  • 実践 臨床生殖免疫学

    BANNO KOUJI, 中外医学社, 2018.05

    Scope: 子宮移植

  • 臨床医とための最新産科婦人科

    BANNO KOUJI, 先端医療技術研究所, 2017.08

    Scope: 子宮移植の現状と展望.

  • 慶應義塾大学病院の医師100人と学ぶ病気の予習帳

    BANNO KOUJI, 講談社, 2015.12

    Scope: 子宮筋腫

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Papers 【 Display / hide

  • Upregulation of cyclase-associated actin cytoskeleton regulatory protein 2 in epithelial ovarian cancer correlates with aggressive histologic types and worse outcomes.

    Adachi M, Masugi Y, Yamazaki K, Emoto K, Kobayashi Y, Tominaga E, Banno K, Aoki D, Sakamoto M.

    Japanese Journal of Clinical Oncology  2020.03

    Research paper (scientific journal), Joint Work, Accepted

  • Significance of PD-L1 expression in carbon-iron radiotherapy for uterine cervical adeno/adenosquamous carcinoma.

    Iijima M, Okonogi N, Morokoshi Y, Kanda H, Yamada T, Kobayashi Y, Banno K, Wakatsuki M, Yamada S, Kanda T, Aoki D, Hasegawa S.

    Journal of Gynecologic Oncology 31 ( 2 ) e19. 2020.03

    Research paper (scientific journal), Joint Work, Accepted

  • LAMC1 is a prognostic factor and potential therapeutic target in endometrial cancer.

    Kunitomi H, Kobayashi Y, Wu RC, Takeda T, Tominaga E, Banno K, Aoki D.

    Journal of Gynecologic Oncology 31 ( 2 ) e11. 2020.03

    Research paper (scientific journal), Joint Work, Accepted

  • The insulin-PI3K-Rac1 axis contributes to terminal adipocyte differentiation through regulation of actin cytoskeleton dynamics.

    Kunitomi H, Oki Y, Onishi N, Kano K, Banno K, Aoki D, Saya H, Nobuse H.

    Genes Cells (Genes to Cells)  25 ( 3 ) 165 - 174 2020.01

    Research paper (scientific journal), Accepted,  ISSN  13569597

     View Summary

    © 2020 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd Adipocyte differentiation is accompanied by a pronounced change in the actin cytoskeleton characterized by the reorganization of filamentous (F)-actin stress fibers into cortical F-actin structures. We previously showed that depolymerization of F-actin stress fibers induced by inactivation of RhoA–ROCK (Rho-associated kinase) signaling acts as a trigger for adipocyte differentiation. The relevance and underlying mechanism of the formation of cortical F-actin structures from depolymerized actin during adipocyte differentiation have remained unclear, however. We have now examined the mechanistic relation between actin dynamics and adipogenic induction. Transient exposure to the actin-depolymerizing agent latrunculin A (LatA) supported the formation of adipocyte-associated cortical actin structures and the completion of terminal adipocyte differentiation in the presence of insulin, whereas long-term exposure to LatA prevented such actin reorganization as well as terminal adipogenesis. Moreover, these effects of insulin were prevented by inhibition of phosphatidylinositol 3-kinase (PI3K)–Rac1 signaling and the actin-related protein 2/3 (Arp2/3) complex which is a critical component of the cortical actin networks. Our findings thus suggest that the insulin-PI3K-Rac1 axis leads to the formation of adipocyte-associated cortical actin structures which is essential for the completion of adipocyte differentiation.

  • Primary malignant melanoma of the uterine cervix or vigina which were successfully treated with nivormab.

    Anko M, Nakamura M, Kobayashi Y, Tsuji K, Nakada S, Nakamura Y, Funakoshi T, Banno K, Aoki D.

    J Obstet Gynaecol Res 46 ( 1 ) 190 - 195 2020.01

    Research paper (scientific journal), Joint Work, Accepted

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Papers, etc., Registered in KOARA 【 Display / hide

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Reviews, Commentaries, etc. 【 Display / hide

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Presentations 【 Display / hide

  • 子宮肉腫の薬物療法における新たなトレンド

    阪埜浩司

    福井県肉腫治療研究会 (福井県福井市 福井県医師会館) , 2020.02, Public discourse, seminar, tutorial, course, lecture and others

  • 子宮肉腫の薬物療法における新たなトレンド

    阪埜浩司

    Sarcoma Conference in Shiga (滋賀県草津市 クサツホテルエストピア) , 2020.01, Public discourse, seminar, tutorial, course, lecture and others

  • 婦人科腫瘍としてのリンチ症候群〜婦人科腫瘍医の視点から〜

    阪埜浩司

    第5回日本産婦人科遺伝診療学会学術講演会 (東京都港区赤坂 国際医療福祉大学 東京赤坂キャンパス) , 2019.12, Symposium, Workshop, Panelist (nomination)

  • ライフステージを意識した実践的子宮内膜症・腺筋症治療 2019

    阪埜浩司

    桃花会学術講演会 (岩手県盛岡市 愛宕 堀岡グランドホテル) , 2019.11, Public discourse, seminar, tutorial, course, lecture and others

  • 子宮筋腫の最新薬物療法としての経口GnRHアンタゴニスト製剤

    阪埜浩司

    第65回日本生殖医学会学術講演会・総会 (兵庫県神戸市 神戸国際会議場) , 2019.11, Oral Presentation(guest/special)

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Research Projects of Competitive Funds, etc. 【 Display / hide

  • エピゲノム異常を標的とした子宮内膜癌の新たな診断・治療法の探索

    2016.04
    -
    2019.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 阪埜 浩司, Grant-in-Aid for Scientific Research (C), Principal Investigator

  • ラットにおける半導体レーザー手術装置に関する基礎的研究

    2009.12
    -
    Present

    Commissioned research

  • 子宮内膜症に関する創薬標的の探索および疾患モデルの構築

    2009.10
    -
    Present

    Joint research

Awards 【 Display / hide

  • 平成25年度 日本医師会医学研究奨励賞

    BANNO KOUJI, 2013.11

  • 平成24年度 日本産科婦人科学会学術奨励賞

    BANNO KOUJI, 2012.12, 子宮体癌におけるジェネティクスとエピジェネティクス 〜子宮内膜の発癌とDNAミスマッチ修復遺伝子異常との関連を中心に〜

  • 平成23年度 医学部Best Teacher Award

    BANNO KOUJI, 2012.07

    Type of Award: Keio commendation etc.

  • 平成22年度 医学部Best Teacher Award

    BANNO KOUJI, 2011.06

    Type of Award: Keio commendation etc.

  • 平成21年度 医学部 Best Teacher Award

    BANNO KOUJI, 2010.03

    Type of Award: Keio commendation etc.

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Courses Taught 【 Display / hide

  • LECTURE SERIES, GYNECOLOGY

    2019

  • 大学院修士講義

    2019, Major subject, Lecture, Within own faculty

Courses Previously Taught 【 Display / hide

  • 婦人科 臨床実習

    Keio University, 2015, Full academic year, Major subject, Seminar, Lecturer outside of Keio, 5h, 100people

  • 大学院特別講義 臨床腫瘍学

    Keio University, 2015, Full academic year, Major subject, Lecture, Within own faculty, 30people

    家族性腫瘍

  • 婦人科学

    Keio University, 2015, Spring Semester, Major subject, Lecture, Within own faculty, 100people

  • 婦人科学 臨床実習

    Keio University, 2014, Full academic year, Major subject, Laboratory work/practical work/exercise, Within own faculty

  • 大学院講義 臨床腫瘍学

    Keio University, 2014, Full academic year, Other, Lecture, Within own faculty

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Educational Activities and Special Notes 【 Display / hide

  • 大学院特別講義 臨床腫瘍学

    2015.11
    -
    Present

    , Special Affairs

  • 婦人科学

    2015.09
    -
    Present

    , Special Affairs

  • 婦人科臨床実習

    2015.05
    -
    2015.12

    , Special Affairs

 

Social Activities 【 Display / hide

  • 日本子宮移植研究会

    2014.03
    -
    Present
  • 日本学術会議

    2007.01
    -
    2008.04
  • 女性の健康基金

    2005
    -
    2006

Memberships in Academic Societies 【 Display / hide

  • 日本家族性腫瘍学会, 

    2009.01
    -
    Present
  • 日本医師会総合政策研究機構, 

    2007.01
    -
    2008.09
  • 日本癌治療学会, 

    2002
    -
    Present
  • 日本臨床細胞学会, 

    2002
    -
    Present
  • 日本婦人科腫瘍学会, 

    2002
    -
    Present

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Committee Experiences 【 Display / hide

  • 2014.03
    -
    Present

    Director, 日本子宮移植研究会

  • 2009.01
    -
    Present

    Board of Councillors, 日本家族性腫瘍学会

  • 2009.01
    -
    2016.10

    編集委員, 日本家族性腫瘍学会

  • 2007.01
    -
    2008.09

    客員研究員, 日本医師会総合政策研究機構

  • 2007.01
    -
    2008.04

    上席学術調査員, 日本学術会議

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