Details of a Researcher - Banno, Koji

Banno, Koji

写真a

Affiliation: School of Medicine, Department of Obstetrics and Gynecology (Gynecology) （Shinanomachi）

Position: Associate Professor

E-mail Address

External Links

Career 【 Display / hide 】

1992.05

-

Present

慶應義塾大学病院研修医
1995.07

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Present

慶應義塾大学助手(医学部産婦人科学）
1996.04

-

2000.03

癌研究会癌研究所細胞生物部研究生
2001.06

-

Present

慶應義塾大学助手（医学部産婦人科学）
2005.04

-

Present

慶應義塾大学助手（医学部産婦人科学・外来医長）

Academic Background 【 Display / hide 】

1992

Keio University, Faculty of Medicine

University, Graduated
2000

Keio University, Graduate School, Division of Medicine, 婦人科腫瘍学・細胞生物学

Graduate School, Completed, Doctoral course

Academic Degrees 【 Display / hide 】

博士（医学）, Keio University, Coursework

Licenses and Qualifications 【 Display / hide 】

日本臨床細胞学会　指導医
日本婦人科腫瘍学会　専門医
がん治療暫定教育医
がん治療認定医
日本婦人科腫瘍学会指導医

Research Areas 【 Display / hide 】

Human genetics
Obstetrics and gynecology

Research Keywords 【 Display / hide 】

エピジェネテイクス
子宮体癌
子宮内膜
子宮移植
家族性腫瘍

Books 【 Display / hide 】

Nonhuman Primate Research in Uterus Transplantation.

Kisu I, Banno K, Matoba Y, Aoki D. , Splinger, 2020.01

Scope: Nonhuman Primate Research in Uterus Transplantation., Contact page： 57-67
Cell Biology of the Ovary, Stem Cells, Development, Cancer, and Clinical Aspects

Kobayashi Y, Nomura H, Kataoka F, Tominaga E, Banno K, Aoki D, USA: Springer, 2018.05

Scope: Clinical Management of Epithelial Ovarian Cancer.
実践　臨床生殖免疫学

BANNO KOUJI, 中外医学社, 2018.05

Scope: 子宮移植
臨床医とための最新産科婦人科

BANNO KOUJI, 先端医療技術研究所, 2017.08

Scope: 子宮移植の現状と展望.
慶應義塾大学病院の医師100人と学ぶ病気の予習帳

BANNO KOUJI, 講談社, 2015.12

Scope: 子宮筋腫

Papers 【 Display / hide 】

Upregulation of cyclase-associated actin cytoskeleton regulatory protein 2 in epithelial ovarian cancer correlates with aggressive histologic types and worse outcomes.

Adachi M, Masugi Y, Yamazaki K, Emoto K, Kobayashi Y, Tominaga E, Banno K, Aoki D, Sakamoto M.

Japanese Journal of Clinical Oncology 2020.03

Research paper (scientific journal), Joint Work, Accepted
Significance of PD-L1 expression in carbon-iron radiotherapy for uterine cervical adeno/adenosquamous carcinoma.

Iijima M, Okonogi N, Morokoshi Y, Kanda H, Yamada T, Kobayashi Y, Banno K, Wakatsuki M, Yamada S, Kanda T, Aoki D, Hasegawa S.

Journal of Gynecologic Oncology 31 （ 2 ） e19. 2020.03

Research paper (scientific journal), Joint Work, Accepted
LAMC1 is a prognostic factor and potential therapeutic target in endometrial cancer.

Kunitomi H, Kobayashi Y, Wu RC, Takeda T, Tominaga E, Banno K, Aoki D.

Journal of Gynecologic Oncology 31 （ 2 ） e11. 2020.03

Research paper (scientific journal), Joint Work, Accepted
The insulin-PI3K-Rac1 axis contributes to terminal adipocyte differentiation through regulation of actin cytoskeleton dynamics.

Kunitomi H, Oki Y, Onishi N, Kano K, Banno K, Aoki D, Saya H, Nobuse H.

Genes Cells （Genes to Cells) 25 （ 3 ） 165 - 174 2020.01

Research paper (scientific journal), Accepted, ISSN 13569597

　View Summary

© 2020 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd Adipocyte differentiation is accompanied by a pronounced change in the actin cytoskeleton characterized by the reorganization of filamentous (F)-actin stress fibers into cortical F-actin structures. We previously showed that depolymerization of F-actin stress fibers induced by inactivation of RhoA–ROCK (Rho-associated kinase) signaling acts as a trigger for adipocyte differentiation. The relevance and underlying mechanism of the formation of cortical F-actin structures from depolymerized actin during adipocyte differentiation have remained unclear, however. We have now examined the mechanistic relation between actin dynamics and adipogenic induction. Transient exposure to the actin-depolymerizing agent latrunculin A (LatA) supported the formation of adipocyte-associated cortical actin structures and the completion of terminal adipocyte differentiation in the presence of insulin, whereas long-term exposure to LatA prevented such actin reorganization as well as terminal adipogenesis. Moreover, these effects of insulin were prevented by inhibition of phosphatidylinositol 3-kinase (PI3K)–Rac1 signaling and the actin-related protein 2/3 (Arp2/3) complex which is a critical component of the cortical actin networks. Our findings thus suggest that the insulin-PI3K-Rac1 axis leads to the formation of adipocyte-associated cortical actin structures which is essential for the completion of adipocyte differentiation.
- Access to Document (DOI)
Primary malignant melanoma of the uterine cervix or vigina which were successfully treated with nivormab.

Anko M, Nakamura M, Kobayashi Y, Tsuji K, Nakada S, Nakamura Y, Funakoshi T, Banno K, Aoki D.

J Obstet Gynaecol Res 46 （ 1 ） 190 - 195 2020.01

Research paper (scientific journal), Joint Work, Accepted

Papers, etc., Registered in KOARA 【 Display / hide 】

Sensitivities for anti-cancer drugs/hormones for endometrial cancer : from the viewpoint of tumor immunology

Banno, Kōji

科学研究費補助金研究成果報告書 2018
The study of novel diagnosis and treatment for endometrial cancer targeting aberrant DNA methylation

Banno, Kōji

科学研究費補助金研究成果報告書 2018
Translational research for clinical application using statins as a prevention drugs against ovarian cancer

Banno, Koji

科学研究費補助金研究成果報告書 2017
Genome-wide DNA methylation analysis in endometrial cancer

Banno, Kōji

科学研究費補助金研究成果報告書 2017
Alteration of tumor immunity and anti-cancer drug/hormone sensitivity in endometrial cancer with frequent MMR mechanism abnormality

Banno, Koji

科学研究費補助金研究成果報告書 2015

Reviews, Commentaries, etc. 【 Display / hide 】

Re: Rethinking the time interval to embryo transfer after uterus transplantation – DUETS (Dallas UtErus Transplant Study)

Kisu I., Banno K., Aoki D.

BJOG: An International Journal of Obstetrics and Gynaecology (BJOG: An International Journal of Obstetrics and Gynaecology) 126 ( 12 ) 1508 - 1509 2019.11

ISSN 14700328
- Access to Document (DOI)
Uterus transplantation: advantages and disadvantages of a deceased donor

Kisu I., Banno K., Matoba Y., Aoki D.

Archives of gynecology and obstetrics (Archives of gynecology and obstetrics) 299 ( 5 ) 1213 - 1214 2019.05
- Access to Document (DOI)
子宮移植. 子宮移植手技.

BANNO KOUJI

産婦人科の実際 67 ( 11 ) 1559 - 1567 2018.10

Introduction and explanation (commerce magazine)
簡便でストレスのないリデューサースリーブを用いたセプラフィルム挿入法の工夫.

BANNO KOUJI

産婦人科の実際 67 ( 10 ) 1165 - 1170 2018.10

Introduction and explanation (commerce magazine)
子宮がん（頸がん・体がん）

BANNO KOUJI

Credentials 121 22 - 25 2018.10

Introduction and explanation (commerce magazine), Single Work

Presentations 【 Display / hide 】

子宮肉腫の薬物療法における新たなトレンド

阪埜浩司

福井県肉腫治療研究会 (福井県福井市　福井県医師会館) , 2020.02, Public discourse, seminar, tutorial, course, lecture and others
子宮肉腫の薬物療法における新たなトレンド

阪埜浩司

Sarcoma Conference in Shiga (滋賀県草津市　クサツホテルエストピア) , 2020.01, Public discourse, seminar, tutorial, course, lecture and others
婦人科腫瘍としてのリンチ症候群〜婦人科腫瘍医の視点から〜

阪埜浩司

第5回日本産婦人科遺伝診療学会学術講演会 (東京都港区赤坂　国際医療福祉大学　東京赤坂キャンパス) , 2019.12, Symposium, Workshop, Panelist (nomination)
ライフステージを意識した実践的子宮内膜症・腺筋症治療 2019

阪埜浩司

桃花会学術講演会 (岩手県盛岡市　愛宕　堀岡グランドホテル) , 2019.11, Public discourse, seminar, tutorial, course, lecture and others
子宮筋腫の最新薬物療法としての経口GnRHアンタゴニスト製剤

阪埜浩司

第65回日本生殖医学会学術講演会・総会 (兵庫県神戸市　神戸国際会議場) , 2019.11, Oral Presentation(guest/special)

Research Projects of Competitive Funds, etc. 【 Display / hide 】

エピゲノム異常を標的とした子宮内膜癌の新たな診断・治療法の探索

2016.04

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2019.03

MEXT,JSPS, Grant-in-Aid for Scientific Research, 阪埜　浩司, Grant-in-Aid for Scientific Research (C), Principal Investigator
ラットにおける半導体レーザー手術装置に関する基礎的研究

2009.12

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Present

Commissioned ｒesearch
子宮内膜症に関する創薬標的の探索および疾患モデルの構築

2009.10

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Present

Joint research

Awards 【 Display / hide 】

平成25年度日本医師会医学研究奨励賞

BANNO KOUJI, 2013.11
平成24年度　日本産科婦人科学会学術奨励賞

BANNO KOUJI, 2012.12, 子宮体癌におけるジェネティクスとエピジェネティクス〜子宮内膜の発癌とDNAミスマッチ修復遺伝子異常との関連を中心に〜
平成23年度　医学部Best Teacher Award

BANNO KOUJI, 2012.07

Type of Award： Keio commendation etc.
平成22年度　医学部Best Teacher Award

BANNO KOUJI, 2011.06

Type of Award： Keio commendation etc.
平成21年度　医学部 Best Teacher Award

BANNO KOUJI, 2010.03

Type of Award： Keio commendation etc.

Courses Taught 【 Display / hide 】

LECTURE SERIES, GYNECOLOGY

2019
大学院修士講義

2019, Major subject, Lecture, Within own ｆaculty

Courses Previously Taught 【 Display / hide 】

婦人科臨床実習

Keio University, 2015, Full academic year, Major subject, Seminar, Lecturer outside of Keio, 5h, 100people
大学院特別講義臨床腫瘍学

Keio University, 2015, Full academic year, Major subject, Lecture, Within own ｆaculty, 30people

家族性腫瘍
婦人科学

Keio University, 2015, Spring Semester, Major subject, Lecture, Within own ｆaculty, 100people
婦人科学臨床実習

Keio University, 2014, Full academic year, Major subject, Laboratory work/practical work/exercise, Within own ｆaculty
大学院講義臨床腫瘍学

Keio University, 2014, Full academic year, Other, Lecture, Within own ｆaculty

Educational Activities and Special Notes 【 Display / hide 】

大学院特別講義臨床腫瘍学

2015.11

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Present

, Special Affairs
婦人科学

2015.09

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Present

, Special Affairs
婦人科臨床実習

2015.05

-

2015.12

, Special Affairs

Social Activities 【 Display / hide 】

日本子宮移植研究会

2014.03

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Present
日本学術会議

2007.01

-

2008.04
女性の健康基金

2005

-

2006

Memberships in Academic Societies 【 Display / hide 】

日本家族性腫瘍学会,

2009.01

-

Present
日本医師会総合政策研究機構,

2007.01

-

2008.09
日本癌治療学会,

2002

-

Present
日本臨床細胞学会,

2002

-

Present
日本婦人科腫瘍学会,

2002

-

Present

Committee Experiences 【 Display / hide 】

2014.03

-

Present

Director, 日本子宮移植研究会
2009.01

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Present

Board of Councillors, 日本家族性腫瘍学会
2009.01

-

2016.10

編集委員, 日本家族性腫瘍学会
2007.01

-

2008.09

客員研究員, 日本医師会総合政策研究機構
2007.01

-

2008.04

上席学術調査員, 日本学術会議