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Affiliation
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School of Medicine, Department of Anesthesiology (Shinanomachi)
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Position
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Instructor
Toramaru, Tomoko
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Papers 【 Display / hide 】
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Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment
Oyaizu-Toramaru T, Suhara T, Hayakawa N, Nakamura T, Kubo A, Minamishima S, Yamaguchi K, Hishiki T, Morisaki H, Suematsu M, Minamishima YA
Molecular and Cellular Biology 37 ( 16 ) e00248-17 2017.08
Research paper (scientific journal), Joint Work, Accepted
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Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
Suhara T, Hishiki T, Kasahara M, Hayakawa N, Oyaizu T, Nakanishi T, Kubo A, Morisaki H, Kaelin WG Jr, Suematsu M, Minamishima YA
Proceedings of the National Academy of Sciences of the United States of America 112 ( 37 ) 11642 - 11647 2015.09
Research paper (scientific journal), Joint Work, Accepted
Papers, etc., Registered in KOARA 【 Display / hide 】
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Elucidating the relevance of pathological chronic pain and hypoxic response
Toramaru, Tomoko
科学研究費補助金研究成果報告書 2021
Reviews, Commentaries, etc. 【 Display / hide 】
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その低血圧, そのままで大丈夫? ～術中低血圧が引き起こす病態たち～
寅丸智子, 他
臨床麻酔 2020.04
Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
Presentations 【 Display / hide 】
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プロリン水酸化酵素阻害はマウス手術後痛モデル創部で神経障害を惹起する
寅丸智子, 加藤純悟, 魯方琳, 藤田治人, 森崎浩
第68回日本麻酔科学会学術集会,
2021.06,Poster presentation
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マウスモデルによる虚血肢痛における低酸素応答関連分子の関与の検討
寅丸智子, 加藤純悟, 魯方琳, 曲徳泰, 南嶋しづか, 森﨑浩
第67回日本麻酔科学会学術集会,
2020.07,Poster presentation
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Targeting oxygen sensing prolyl hydroxylase (PHD) for metformin-associated lactic acidosis (MALA) treatment
TORAMARU Tomoko
Japanese Society of Anesthesiologists (兵庫県神戸市) ,
2017.06,Poster presentation, 日本麻酔科学会
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Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis
TORAMARU Tomoko
The Japanese Association for Hypoxia Biology,
2016.07,Oral presentation (general)
Research Projects of Competitive Funds, etc. 【 Display / hide 】
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マウス術後複合性局所疼痛症候群モデルにおける中枢性感作の可視化と治療標的の探索
2022.04-2025.03MEXT,JSPS, Grant-in-Aid for Scientific Research, 若手研究, Principal investigator
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低酸素応答を介した病的疼痛の重症化・慢性化の機序の解明
2019.04-2022.03MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists , Principal investigator
Intellectual Property Rights, etc. 【 Display / hide 】
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Drug for preventing or treating lactic acidosis
Date applied： 2016-78492 2016.04
Patent, Joint
Awards 【 Display / hide 】
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Young investigator award
Oyaizu–Toramaru T, Suhara T, Hayakawa N, Nakamura T, Kubo A, Minamishima S, Yamaguchi K, Hishiki T, Morisaki H, Suematsu M, Minamishima YA, 2016.07, The Japanese Association for Hypoxia Biology, Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis
Memberships in Academic Societies 【 Display / hide 】
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Japanese Society of Anesthesiologists,
2008.04-Present