Toramaru, Tomoko

写真a

Affiliation

School of Medicine, Department of Anesthesiology (Shinanomachi)

Position

Instructor

Academic Degrees 【 Display / hide

  • 博士(医学), Keio University, Coursework, 2018.03

 

Research Areas 【 Display / hide

  • Anesthesiology

Research Keywords 【 Display / hide

  • Anesthesiology Hypoxia

Research Themes 【 Display / hide

  • Anesthesiology Hypoxia, 

    2014.04
    -
    Present

 

Papers 【 Display / hide

  • Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment

    Oyaizu-Toramaru T, Suhara T, Hayakawa N, Nakamura T, Kubo A, Minamishima S, Yamaguchi K, Hishiki T, Morisaki H, Suematsu M, Minamishima YA

    Molecular and Cellular Biology 37 ( 16 ) e00248-17 2017.08

    Research paper (scientific journal), Joint Work, Accepted

  • Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle

    Suhara T, Hishiki T, Kasahara M, Hayakawa N, Oyaizu T, Nakanishi T, Kubo A, Morisaki H, Kaelin WG Jr, Suematsu M, Minamishima YA

    Proceedings of the National Academy of Sciences of the United States of America 112 ( 37 ) 11642 - 11647 2015.09

    Research paper (scientific journal), Joint Work, Accepted

Papers, etc., Registered in KOARA 【 Display / hide

Reviews, Commentaries, etc. 【 Display / hide

  • その低血圧, そのままで大丈夫? ~術中低血圧が引き起こす病態たち~

    寅丸智子, 他

    臨床麻酔  2020.04

    Introduction and explanation (commerce magazine)

Presentations 【 Display / hide

  • プロリン水酸化酵素阻害はマウス手術後痛モデル創部で神経障害を惹起する

    寅丸智子, 加藤純悟, 魯方琳, 藤田治人, 森崎浩

    第68回日本麻酔科学会学術集会, 2021.06, Poster (general)

  • マウスモデルによる虚血肢痛における低酸素応答関連分子の関与の検討

    寅丸智子, 加藤純悟, 魯方琳, 曲徳泰, 南嶋しづか, 森﨑浩

    第67回日本麻酔科学会学術集会, 2020.07, Poster (general)

  • Targeting oxygen sensing prolyl hydroxylase (PHD) for metformin-associated lactic acidosis (MALA) treatment

    TORAMARU Tomoko

    Japanese Society of Anesthesiologists (兵庫県神戸市) , 2017.06, Poster (general), 日本麻酔科学会

  • Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis

    TORAMARU Tomoko

    The Japanese Association for Hypoxia Biology, 2016.07, Oral Presentation(general)

Research Projects of Competitive Funds, etc. 【 Display / hide

  • 低酸素応答を介した病的疼痛の重症化・慢性化の機序の解明

    2019.04
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 寅丸 智子, Grant-in-Aid for Early-Career Scientists , Principal Investigator

Intellectual Property Rights, etc. 【 Display / hide

  • Drug for preventing or treating lactic acidosis

    Application No.: 2016-78492  2016.04 

    Patent, Joint

Awards 【 Display / hide

  • Young investigator award

    Oyaizu–Toramaru T, Suhara T, Hayakawa N, Nakamura T, Kubo A, Minamishima S, Yamaguchi K, Hishiki T, Morisaki H, Suematsu M, Minamishima YA, 2016.07, The Japanese Association for Hypoxia Biology, Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis

 

Memberships in Academic Societies 【 Display / hide

  • Japanese Society of Anesthesiologists, 

    2008.04
    -
    Present