Papers - Hayashida, Tetsu

Actionable gene alterations in an Asian population with triple-negative breast cancer.

Nagahashi M, Ling Y, Hayashida T, Kitagawa Y, Futamura M, Yoshida K, Kuwayama T, Nakamura S, Toshikawa C, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Miyoshi Y, Tsuchida J, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Takabe K, Okuda S, Wakai T

JCO precision oncology 2 2018

Joint Work

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Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.

Shimada Y, Kameyama H, Nagahashi M, Ichikawa H, Muneoka Y, Yagi R, Tajima Y, Okamura T, Nakano M, Sakata J, Kobayashi T, Nogami H, Maruyama S, Takii Y, Hayashida T, Takaishi H, Kitagawa Y, Oki E, Konishi T, Ishida F, Kudo SE, Ring JE, Protopopov A, Lyle S, Ling Y, Okuda S, Ishikawa T, Akazawa K, Takabe K, Wakai T

Oncotarget 8 ( 55 ) 93567 - 93579 2017.11

Research paper (scientific journal), Joint Work, Accepted

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Downregulation of cytochrome <i>c</i> oxidase 1 induced radioresistance in esophageal squamous cell carcinoma.

Takesue T, Kawakubo H, Hayashida T, Tsutsui M, Miyao K, Fukuda K, Nakamura R, Takahashi T, Wada N, Takeuchi H, Kitagawa Y

Oncology letters 14 ( 4 ) 4220 - 4224 2017.10

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1792-1074

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The use of laparoscopic rectopexy to manage rectal prolapse with Pseudo-Meigs' syndrome in a 64-year-old female: a case report.

Kondo T, Tsuruta M, Hasegawa H, Okabayashi K, Shigeta K, Hayashida T, Kitagawa Y

Clinical case reports 5 ( 5 ) 642 - 644 2017.05

Research paper (scientific journal), Joint Work, Accepted,  ISSN  2050-0904

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Self-rated cognitive functions following chemotherapy in patients with breast cancer: a 6-month prospective study.

Kitahata R, Nakajima S, Uchida H, Hayashida T, Takahashi M, Nio S, Hirano J, Nagaoka M, Suzuki T, Jinno H, Kitagawa Y, Mimura M

Neuropsychiatric disease and treatment 13   2489 - 2496 2017

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1176-6328

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Biological markers of invasive breast cancer.

Matsumoto A, Jinno H, Ando T, Fujii T, Nakamura T, Saito J, Takahashi M, Hayashida T, Kitagawa Y

Japanese journal of clinical oncology 46 ( 2 ) 99 - 105 2016.02

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0368-2811

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A randomized controlled study comparing a vessel sealing system with the conventional technique in axillary lymph node dissection for primary breast cancer.

Seki T, Hayashida T, Takahashi M, Jinno H, Kitagawa Y

SpringerPlus 5 ( 1 ) 1004 2016

Research paper (scientific journal), Joint Work, Accepted,  ISSN  2193-1801

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Technical feasibility of sentinel lymph node biopsy in patients with ipsilateral breast tumor recurrence and previous axillary surgery.

Matsumoto A, Jinno H, Nakamura T, Saito J, Takahashi M, Hayashida T, Kameyama K, Kitagawa Y

International journal of surgery (London, England) 22   28 - 31 2015.10

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1743-9191

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Comprehensive screening of genes resistant to an anticancer drug in esophageal squamous cell carcinoma.

Tsutsui M, Kawakubo H, Hayashida T, Fukuda K, Nakamura R, Takahashi T, Wada N, Saikawa Y, Omori T, Takeuchi H, Kitagawa Y

International journal of oncology 47 ( 3 ) 867 - 74 2015.09

Joint Work,  ISSN  1019-6439

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Prognostic implications of receptor discordance between primary and recurrent breast cancer.

Matsumoto A, Jinno H, Murata T, Seki T, Takahashi M, Hayashida T, Kameyama K, Kitagawa Y

International journal of clinical oncology 20 ( 4 ) 701 - 8 2015.08

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1341-9625

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Comparison of oncological safety between nipple sparing mastectomy and total mastectomy using propensity score matching.

Seki T, Jinno H, Okabayashi K, Murata T, Matsumoto A, Takahashi M, Hayashida T, Kitagawa Y

Annals of the Royal College of Surgeons of England 97 ( 4 ) 291 - 7 2015.05

Joint Work,  ISSN  0035-8843

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Gene transfer of high-mobility group box 1 box-A domain in a rat acute liver failure model.

Tanaka M, Shinoda M, Takayanagi A, Oshima G, Nishiyama R, Fukuda K, Yagi H, Hayashida T, Masugi Y, Suda K, Yamada S, Miyasho T, Hibi T, Abe Y, Kitago M, Obara H, Itano O, Takeuchi H, Sakamoto M, Tanabe M, Maruyama I, Kitagawa Y

The Journal of surgical research 194 ( 2 ) 571 - 80 2015.04

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0022-4804

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Response.

Nagayama A, Hayashida T, Jinno H, Takahashi M, Kitagawa Y

Journal of the National Cancer Institute 107 ( 4 )  2015.04

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0027-8874

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単純ヘルペスウイルスの再活性化による口腔内・食道潰瘍を呈した薬剤性過敏症症候群の1例

森本 亜里, 舩越 建, 福島 彩乃, 久保 亮治, 海老原 全, 林田 哲, 真杉 洋平, 亀山 香織, 永尾 圭介

臨床皮膚科 ((株)医学書院)  68 ( 11 ) 873 - 878 2014.10

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0021-4973

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59歳,女性.乳癌脳転移摘出術後,ゾニサミドを開始した40日後より膝に紅斑が出現し全身に拡大した.初診時,38℃の発熱,顔面の潮紅・腫脹,全身に半米粒大までの紅斑の多発,頬粘膜びらんを認めた.頸部・鼠径部リンパ節腫脹,白血球11,100/μl,好酸球36%,肝酵素はAST 102IU/l,ALT 97IU/lと上昇し,ゾニサミドによる薬剤性過敏症症候群(drug-induced hypersensitivity syndrome:DIHS)と診断し,プレドニゾロン(PSL)60mg/日を開始した.一旦軽快したが発症16日目に発熱,皮疹,口腔内びらんが再燃し,肝酵素値もAST 97IU/ml,ALT 117IU/mlと増悪した.DIHSの2峰目と判断しPSL同量を継続したが口唇・歯肉びらんのみが遷延した.発症25日目に舌潰瘍が多発し,食道潰瘍を認めた.舌・食道の生検組織像で核内封入体を認め,免疫組織染色で単純ヘルペスウイルス(herpes simplex syndrome:HSV)陽性であった.発症30日目ヒトヘルペスウイルス6型(human herpes virus-6:HHV-6)の抗体価上昇およびゾニサミドの薬剤リンパ球刺激試験陽性化がみられた.HSVはHHV-6とともにDIHSの病態に関与するヘルペスウイルス科の1つと考えた.(著者抄録)

Comparative effectiveness of neoadjuvant therapy for HER2-positive breast cancer: a network meta-analysis.

Nagayama A, Hayashida T, Jinno H, Takahashi M, Seki T, Matsumoto A, Murata T, Ashrafian H, Athanasiou T, Okabayashi K, Kitagawa Y

Journal of the National Cancer Institute 106 ( 9 )  2014.09

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0027-8874

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Loss of B-cell translocation gene 2 expression in estrogen receptor-positive breast cancer predicts tamoxifen resistance.

Takahashi M, Hayashida T, Okazaki H, Miyao K, Jinno H, Kitagawa Y

Cancer science 105 ( 6 ) 675 - 82 2014.06

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1347-9032

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Bevacizumab terminates homeobox B9-induced tumor proliferation by silencing microenvironmental communication.

Hoshino Y, Hayashida T, Hirata A, Takahashi H, Chiba N, Ohmura M, Wakui M, Jinno H, Hasegawa H, Maheswaran S, Suematsu M, Kitagawa Y

Molecular cancer 13   102 2014.05

Research paper (scientific journal), Joint Work, Accepted

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Cetuximab-mediated ADCC activity is correlated with the cell surface expression level of EGFR but not with the KRAS/BRAF mutational status in colorectal cancer.

Seo Y, Ishii Y, Ochiai H, Fukuda K, Akimoto S, Hayashida T, Okabayashi K, Tsuruta M, Hasegawa H, Kitagawa Y

Oncology reports 31 ( 5 ) 2115 - 22 2014.05

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1021-335X

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An E2F1-HOXB9 transcriptional circuit is associated with breast cancer progression.

Zhussupova A, Hayashida T, Takahashi M, Miyao K, Okazaki H, Jinno H, Kitagawa Y

PloS one 9 ( 8 ) e105285 2014

Research paper (scientific journal), Joint Work, Accepted

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HMGB1制御による急性肝不全に対する新治療の開発　診療に役立つ治療法の研究

篠田 昌宏, 田邉 稔, 大島 剛, 高野 公徳, 西山 亮, 田中 真之, 林田 哲, 八木 洋, 阿部 雄太, 北郷 実, 田中 克典, 尾原 秀明, 板野 理, 須田 康一, 竹内 裕也, 河地 茂行, 北川 雄光

日本腹部救急医学会雑誌 ((一社)日本腹部救急医学会)  33 ( 3 ) 535 - 542 2013.03

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1340-2242

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われわれは,各種病態において炎症性メディエーターとして注目されているHigh-mobility group box 1(HMGB1)に着目し,劇症肝不全に対する新治療の開発を試みている。劇症肝不全患者,薬剤誘導性ラット劇症肝不全モデルにおいて血漿中HMGB1,肝組織中HMGB1は健常群に比較してそれぞれ有意な上昇,低下を認めた。HMGB1に対する特異的中和抗体を薬剤誘導性ラット劇症肝不全モデルに投与したところ著明な病態改善効果を認めた。さらに,HMGB1の阻害剤であるBox Aタンパクの遺伝子導入,リコンビナントトロンボモジュリン投与,HMGB1吸着カラムを用いた体外循環などの有効性を大小の動物モデルで検証した。遺伝子導入,体外循環治療では一定の効果が認められつつあり,診療に役立つ劇症肝不全に対する新治療の開発が期待された。(著者抄録)