論文 - 高月　誠司

診断に苦慮した肺塞栓症―腫瘍塞栓症と思われた4例

佐藤徹，高月誠司，小山田吉孝，安斉俊久，岩永史郎，吉川勉，山口佳寿博，三田村秀雄，小川聡

Therapeutic Research 22 （ 7 ） 1471-1473 2001年07月

研究論文（学術雑誌）, 共著

Recovery of electrophysiological parameters after conversion of atrial fibrillation

Sato Toshiaki, Mitamura Hideo, Kurita Yasuo, Takeshita Akiko, Shinagawa Kaori, Miyoshi Shunichiro, Kanki Hideaki, Hara Motoki, Takatsuki Seiji, Soejima Kyoko, Ogawa Satoshi

International Journal of Cardiology 79 （ 2-3 ） 183-189 2001年07月

研究論文（学術雑誌）, 共著

Catheter ablation of a monofocal premature ventricular complex triggering idiopathic ventricular fibrillation

Takatsuki Seiji, Mitamura Hideo, Ogawa Satoshi

Heart 86 （ 1 ） E3 2001年07月

研究論文（学術雑誌）, 共著

アミオダロン投与によりICD設定に難渋した1例

栗田康生，三田村秀雄，高月誠司，田中美江，大橋成孝，福田有希子，家田真樹，杵渕修，三好俊一郎，原幹，小川聡，小山卓史，村山晃

Progress in Medicine 21 （ suppl 1 ） 1141-1146 2001年05月

研究論文（学術雑誌）, 共著

迷走神経刺激心房細動誘発モデルにおけるKチャネル遮断薬nifekalantとazimilideの薬理学的効果の比較

佐藤俊明，三田村秀雄，竹下晃子，品川香，神吉秀明，高月誠司，小川聡

心電図 21 （ 3 ） 300-307 2001年05月

研究論文（学術雑誌）, 共著

失神精査時に冠動脈攣縮，上室性頻拍及び心室頻拍を認めたARVCの1例

家田真樹，高月誠司，三田村秀雄，大橋成孝，福田友希子，杵渕修，栗田康生，三好俊一郎，原幹，吉川勉，小川聡

Therapeutic Research 22 （ 2 ） 343-352 2001年02月

研究論文（学術雑誌）, 共著

Respiratory cycle-dependent left atrial tachycardia

Takatsuki Seiji, Mitamura Hideo, Miyoshi Shunnichiro, Ogawa Satoshi

Journal of Cardiovascular Electrophysiology 12 （ 10 ） 1202 2001年

ISSN  1045-3873

心不全を併発した心房粗細動例に対するKチャネル遮断薬nifekalantの効果

高月誠司，三田村秀雄，家田真樹，杵渕修，栗田康生，原幹，小川聡

Therapeutic Research 22 （ 4 ） 852-855 2001年

研究論文（学術雑誌）, 共著

植え込み型除細動器

湯浅慎介，高月誠司，三田村秀雄

からだの科学 221 （ 11 ） 101-106 2001年

研究論文（学術雑誌）, 共著

Accessory pathway associated with an anomalous coronary vein in a patient with Wolff-Parkinson-White syndrome

Takatsuki Seiji, Mitamura Hideo, Ieda Masaki, Ogawa Satoshi

Journal of Cardiovascular Electrophysiology 12 （ 9 ） 1080 - 1082 2001年

ISSN  1045-3873

　概要を見る

<p>We report a case of Wolff-Parkinson-White syndrome coexistent with atresia of the coronary sinus (CS) ostium and persistence of the left superior vena cava. The accessory pathway was located at the blind end of the CS, which was bumped with mechanical loss of preexcitation during mapping by a catheter from within the CS. The accessory pathway was successfully ablated with radiofrequency energy applied to this site from the right atrium. This unique combination of anatomically matched anomalies may be important in suggesting a potential embryologic link between the accessory pathway and the coronary vein.</p>

Catheter ablation of a monofocal premature ventricular complex triggering idiopathic ventricular fibrillation.

Takatsuki S., Mitamura H., Ogawa S.

Heart (British Cardiac Society) 86 （ 1 ）  2001年

　概要を見る

<p>A 62 year old man was admitted for evaluation of recurrent episodes of syncope. A surface ECG showed frequent repetitive premature ventricular complexes of right ventricular outflow tract origin. Ventricular fibrillation was inducible by programmed electrical stimulation but otherwise cardiac evaluation was unremarkable. A diagnosis of idiopathic ventricular fibrillation was made and an implantable cardioverter-defibrillator (ICD) was installed. However, spontaneous ventricular fibrillation recurred, requiring repeated ICD discharges. The ventricular fibrillation was reproducibly triggered by a single premature ventricular complex with a specific QRS morphology. Radiofrequency catheter ablation was carried out to eradicate this complex. No ventricular fibrillation has developed after this procedure, and the patient does not require drug treatment.</p>

Efficacy of intravenous nifekalant, a pure Ikr blocker, for atrial tachyarrhythmia with heart failure

Takatsuki S., Mitamura H., Ieda M., Kinebuchi O., Kurita Y., Hara M., Ogawa S.

Therapeutic Research 22 （ 4 ） 852 - 855 2001年

ISSN  0289-8020

　概要を見る

<p>We describe 2 cases of congestive heart failure due to atrial tachyarrhythmias, which were successfully treated by a new Ikr blocker, nifekalant. Case 1 was 59-year old male with congestive heart failure caused by atrial fibrillation with rapid ventricular response due to manifest WPW syndrome. Intravenous administration of nifekalant (0.3mg/kg) successfully slowed ventricular response with reducing the frequency of the pre-excitation. Case 2 was 73-year old male having a history of hypertention, also exhibited heart failure caused by atrial flutter with 2 to 1 or 3 to 1 atrioventricular conduction. The atrial flutter was successfully converted to sinus rhythm with the same dose of intravenous nifekalant. In both cases, the heart failure did not aggravated by the use of nifekalant but recovered soon by treating atrial tachyarrhythmias. Intravenous nifekalant may be a useful option in the management of atrial tachyarrhythmia with heart failure.</p>

Recovery of electrophysiological parameters after conversion of atrial fibrillation

Sato Toshiaki, Mitamura Hideo, Kurita Yasuo, Takeshita Akiko, Shinagawa Kaori, Miyoshi Shunichiro, Kanki Hideaki, Hara Motoki, Takatsuki Seiji, Soejima Kyoko, Ogawa Satoshi

International Journal of Cardiology 79 （ 2-3 ） 183 - 189 2001年

ISSN  0167-5273

　概要を見る

<p>We investigated the recovery of electrophysiological parameters from electrical remodeling after conversion of chronic lone atrial fibrillation in humans. Clinical studies have shown that the longer atrial fibrillation lasts, the more difficult it becomes to maintain the sinus rhythm after cardioversion. To explore the effects of the duration of atrial fibrillation on changes of electrophysiological parameters after conversion, we determined the atrial effective refractory period and P wave duration during right atrial pacing at 1 and 24 h after electrical cardioversion in 15 patients with chronic lone atrial fibrillation (median duration, 6 months). By 24 h after cardioversion, the effective refractory period at a pacing cycle length of 600 ms increased from 225±19 to 254±27 ms. However, the P wave duration did not decrease significantly 24 h after conversion. As the duration of atrial fibrillation became longer, the prolongation of effective refractory period was more delayed (P&lt;0. 001, r=0.82), and the shortening of P wave duration was significantly smaller within 24 h after cardioversion (P&lt;0. 001, r=0.67). After cardioversion of chronic lone atrial fibrillation, the recovery of shortened atrial refractoriness and prolonged intraatrial conduction time is dependent on the duration of preexisting atrial fibrillation. © 2001 Elsevier Science Ireland Ltd. All rights reserved.</p>

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リード不完全断線により洞調律時にショック誤作動を起こしたICD植え込み例

栗田康生，三田村秀雄，高月誠司，前川裕一郎，家田真樹，杵渕修，竹下晃子，原幹，小川聡，三丸敦洋，申範圭，川田志明

心臓 32 （ 12 ） 60-64 2000年12月

研究論文（学術雑誌）, 共著

電気的リモデリングを受けた心房筋の細動誘発性に対する迷走神経緊張の関与

栗田康生，三田村秀雄，竹下晃子，家田真樹，杵渕修，山根明子，佐藤俊明，品川香，神吉秀明，高月誠司，原幹，小川聡

心電図 20 （ 6 ） 628-634 2000年11月

研究論文（学術雑誌）, 共著

Electrophysiologic findings of a patient with inappropriate sinus tachycardia cured by selective radiofrequency catheter ablation

Sato Toshiaki, Mitamura Hideo, Murata Mitsushige, Shinagawa Kaori, Miyoshi Shunichiro, Kanki Hideaki, Takatsuki Seiji, Soejima Kyoko, Miyazaki Toshihisa, Ogawa Satoshi

Journal of Electrocardiology 33 （ 4 ） 381-386 2000年10月

研究論文（学術雑誌）, 共著

心房高頻度刺激による心房の電気的リモデリングおよび心房細動誘発性の経時的変化

竹下晃子，三田村秀雄，栗田康生，品川香，佐藤俊明，家田真樹，杵渕修，神吉秀明，高月誠司，原幹，小川聡

不整脈 16 （ 3 ） 330-336 2000年08月

研究論文（学術雑誌）, 共著

Salutary antiarrhythmic effect of combining a K channel blocker and a beta-blocker in a canine model of 7-day-old myocardial infarction

Takatsuki Seiji, Mitamura Hideo, Kanki Hideaki, Sueyoshi Kouichirou, Ogawa Satoshi

Journal of Cardiovascular Pharmacology 35 （ 6 ） 914-918 2000年06月

研究論文（学術雑誌）, 共著

Diagnostic value of a bedside test for cardiac troponin T in the patient with chest pain presenting to the emergency room

Suzuki Masaru, Hori Shingo, Fujishima Seitaro, Takatsuki Seiji, Nakamura Iwao, Kimura Hiroyuki, Aoki Katsunori, Aikawa Naoki

Keio Journal of Medicine 49 （ 2 ） 74 - 79 2000年06月

ISSN  0022-9717

　概要を見る

<p>Identification of patients with acute chest pain due to acute coronary syndrome is a common and difficult challenge for emergency physicians. A prospective study was conducted to assess the diagnostic value of a bedside test of cardiac troponin T in the emergency room setting. Forty-nine consecutive patients, who visited the emergency room within 6 hours of the onset of acute chest pain, were enrolled. Of the 26 patients who were ultimately diagnosed as having acute coronary syndrome, seven patients (27%) had positive cardiac troponin T assay results, whereas none of the patients without acute coronary syndrome had positive results (0%). For patients with acute coronary syndrome who presented later than 3 hours after the onset (n = 4), the test was positive in all cases (positive predictive value: 100%, negative predictive value: 100%, p &lt; 0.01). However, the positive rate was only 14% for those who presented earlier than 3 hours after the onset (n = 22) (positive predictive value: 100%, negative predictive value: 47%, p = 0.84). In conclusion, bedside troponin T test results should be evaluated considering the time interval from the onset of chest symptoms.</p>

Scilian Gambitに基づく臨床における抗不整脈薬使用の実際

三田村秀雄，高月誠司，三好俊一郎，原幹，小川聡

心電図 20 （ 3 ） 209-217 2000年05月

研究論文（学術雑誌）, 共著