Papers - Honda, Kenya

The microbiota regulates type 2 immunity through RORγt+ T cells

Ohnmacht C, Park JH, Cording S, Wing JB, Atarashi K, Obata Y, Gaboriau-Routhiau V, Marques R, Dulauroy S, Fedoseeva M, Busslinger M, Cerf-Bensussan N, Boneca IG, Voehringer D, Hase K, Honda K, Sakaguchi S, Eberl G

SCIENCE 349 ( 6251 ) 989 - 993 2015.08

Research paper (scientific journal), Joint Work, Accepted

Induction of Th17 cells by segmented filamentous bacteria in the murine intestine.

Farkas AM, Panea C, Goto Y, Nakato G, Galan-Diez M, Narushima S, Honda K, Ivanov ll

J Immunol Methods 421   104 - 111 2015.06

Research paper (scientific journal), Joint Work, Accepted

T-FH-IgA Responses Keep Microbiota in Check

Honda, Kenya

CELL HOST & MICROBE 17 ( 2 ) 144 - 146 2015.02

Research paper (scientific journal),  ISSN  1931-3128

• Access to Document (DOI)

Foxp3(+) T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis

Kawamoto, Shimpei, Maruya, Mikako, Kato, Lucia M., Suda, Wataru, Atarashi, Koji, Doi, Yasuko, Tsutsui, Yumi, Qin, Hongyan, Honda, Kenya, Okada, Takaharu, Hattori, Masahira, Fagarasan, Sidonia

IMMUNITY 41 ( 1 ) 152 - 165 2014.07

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1074-7613

• Access to Document (DOI)

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

Obata, Yuuki, Furusawa, Yukihiro, Endo, Takaho A., Sharif, Jafar, Takahashi, Daisuke, Atarashi, Koji, Nakayama, Manabu, Onawa, Satoshi, Fujimura, Yumiko, Takahashi, Masumi, Ikawa, Tomokatsu, Otsubo, Takeshi, Kawamura, Yuki I., Dohi, Taeko, Tajima, Shoji, Masumoto, Hiroshi, Ohara, Osamu, Honda, Kenya, Hori, Shohei, Ohno, Hiroshi, Koseki, Haruhiko, Hase, Koji

NATURE IMMUNOLOGY 15 ( 6 ) 571 - 579 2014.06

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1529-2908

• Access to Document (DOI)

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Yukihiro, Obata, Yuuki, Fukuda, Shinji, Endo, Takaho A., Nakato, Gaku, Takahashi, Daisuke, Nakanishi, Yumiko, Uetake, Chikako, Kato, Keiko, Kato, Tamotsu, Takahashi, Masumi, Fukuda, Noriko N., Murakami, Shinnosuke, Miyauchi, Eiji, Hino, Shingo, Atarashi, Koji, Onawa, Satoshi, Fujimura, Yumiko, Lockett, Trevor, Clarke, Julie M., Topping, David L., Tomita, Masaru, Hori, Shohei, Ohara, Osamu, Morita, Tatsuya, Koseki, Haruhiko, Kikuchi, Jun, Honda, Kenya, Hase, Koji, Ohno, Hiroshi

NATURE 504 ( 7480 ) 446 - + 2013.12

Research paper (scientific journal),  ISSN  0028-0836

• Access to Document (DOI)

Monocyte-Derived Dendritic Cells Perform Hemophagocytosis to Fine-Tune Excessive Immune Responses

Ohyagi, Hideaki, Onai, Nobuyuki, Sato, Taku, Yotsumoto, Satoshi, Liu, Jiajia, Akiba, Hisaya, Yagita, Hideo, Atarashi, Koji, Honda, Kenya, Roers, Axel, Mueller, Werner, Kurabayashi, Kazutaka, Hosoi-Amaike, Mayuka, Takahashi, Naoto, Hirokawa, Makoto, Matsushima, Kouji, Sawada, Kenichi, Ohteki, Toshiaki

IMMUNITY 39 ( 3 ) 584 - 598 2013.09

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1074-7613

• Access to Document (DOI)

T-reg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Atarashi, Koji, Tanoue, Takeshi, Oshima, Kenshiro, Suda, Wataru, Nagano, Yuji, Nishikawa, Hiroyoshi, Fukuda, Shinji, Saito, Takuro, Narushima, Seiko, Hase, Koji, Kim, Sangwan, Fritz, Joelle V., Wilmes, Paul, Ueha, Satoshi, Matsushima, Kouji, Ohno, Hiroshi, Olle, Bernat, Sakaguchi, Shimon, Taniguchi, Tadatsugu, Morita, Hidetoshi, Hattori, Masahira, Honda, Kenya

NATURE 500 ( 7461 ) 232 - + 2013.08

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0028-0836

• Access to Document (DOI)

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

Yoshimoto, Shin, Loo, Tze Mun, Atarashi, Koji, Kanda, Hiroaki, Sato, Seidai, Oyadomari, Seiichi, Iwakura, Yoichiro, Oshima, Kenshiro, Morita, Hidetoshi, Hattori, Masahisa, Honda, Kenya, Ishikawa, Yuichi, Hara, Eiji, Ohtani, Naoko

NATURE 499 ( 7456 ) 97 - + 2013.07

Research paper (scientific journal),  ISSN  0028-0836

• Access to Document (DOI)

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

Yoshimoto, Shin, Loo, Tze Mun, Atarashi, Koji, Kanda, Hiroaki, Sato, Seidai, Oyadomari, Seiichi, Iwakura, Yoichiro, Oshima, Kenshiro, Morita, Hidetoshi, Hattori, Masahisa, Honda, Kenya, Ishikawa, Yuichi, Hara, Eiji, Ohtani, Naoko

NATURE 499 ( 7456 ) 97 - 101 2013.07

Research paper (scientific journal), Accepted,  ISSN  0028-0836

• Access to Document (DOI)

IRF4 Transcription Factor- Dependent CD11b(+) Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

Schlitzer, Andreas, McGovern, Naomi, Teo, Pearline, Zelante, Teresa, Atarashi, Koji, Low, Donovan, Ho, Adrian W. S., See, Peter, Shin, Amanda, Wasan, Pavandip Singh, Hoeffel, Guillaume, Malleret, Benoit, Heiseke, Alexander, Chew, Samantha, Jardine, Laura, Purvis, Harriet A., Hilkens, Catharien M. U., Tam, John, Poidinger, Michael, Stanley, E. Richard, Krug, Anne B., Renia, Laurent, Sivasankar, Baalasubramanian, Lai Guan Ng, Collin, Matthew, Ricciardi-Castagnoli, Paola, Honda, Kenya, Haniffa, Muzlifah, Ginhoux, Florent

IMMUNITY 38 ( 5 ) 970 - 983 2013.05

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1074-7613

• Access to Document (DOI)

Transcriptional reprogramming of mature CD4(+) helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

Mucida, Daniel, Husain, Mohammad Mushtaq, Muroi, Sawako, van Wijk, Femke, Shinnakasu, Ryo, Naoe, Yoshinori, Reis, Bernardo Sgarbi, Huang, Yujun, Lambolez, Florence, Docherty, Michael, Attinger, Antoine, Shui, Jr-Wen, Kim, Gisen, Lena, Christopher J., Sakaguchi, Shinya, Miyamoto, Chizuko, Wang, Peng, Atarashi, Koji, Park, Yunji, Nakayama, Toshinori, Honda, Kenya, Ellmeier, Wilfried, Kronenberg, Mitchell, Taniuchi, Ichiro, Cheroutre, Hilde

NATURE IMMUNOLOGY 14 ( 3 ) 281 - 289 2013.03

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1529-2908

• Access to Document (DOI)

Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction

Negishi, Hideo, Miki, Shoji, Sarashina, Hana, Taguchi-Atarashi, Naoko, Nakajima, Akira, Matsuki, Kosuke, Endo, Nobuyasu, Yanai, Hideyuki, Nishio, Junko, Honda, Kenya, Taniguchi, Tadatsugu

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109 ( 51 ) 21016 - 21021 2012.12

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0027-8424

• Access to Document (DOI)

Intestinal Commensal Microbes as Immune Modulators

Ivanov, Ivaylo I., Honda, Kenya

CELL HOST & MICROBE 12 ( 4 ) 496 - 508 2012.10

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1931-3128

• Access to Document (DOI)

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses

Negishi, Hideo, Yanai, Hideyuki, Nakajima, Akira, Koshiba, Ryuji, Atarashi, Koji, Matsuda, Atsushi, Matsuki, Kosuke, Miki, Shoji, Doi, Takahiro, Aderem, Alan, Nishio, Junko, Smale, Stephen T., Honda, Kenya, Taniguchi, Tadatsugu

NATURE IMMUNOLOGY 13 ( 7 ) 659 - 666 2012.07

Research paper (scientific journal), Joint Work, Accepted,  ISSN  1529-2908

• Access to Document (DOI)

The Microbiome in Infectious Disease and Inflammation

Honda, Kenya, Littman, Dan R.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 30   759 - 795 2012

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0732-0582

• Access to Document (DOI)

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Atarashi, Koji, Tanoue, Takeshi, Shima, Tatsuichiro, Imaoka, Akemi, Kuwahara, Tomomi, Momose, Yoshika, Cheng, Genhong, Yamasaki, Sho, Saito, Takashi, Ohba, Yusuke, Taniguchi, Tadatsugu, Takeda, Kiyoshi, Hori, Shohei, Ivanov, Ivaylo I., Umesaki, Yoshinori, Itoh, Kikuji, Honda, Kenya

SCIENCE 331 ( 6015 ) 337 - 341 2011.01

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0036-8075

• Access to Document (DOI)

Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus

Savitsky, David A., Yanai, Hideyuki, Tamura, Tomohiko, Taniguchi, Tadatsugu, Honda, Kenya

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 ( 22 ) 10154 - 10159 2010.06

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0027-8424

• Access to Document (DOI)

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

Yanai, Hideyuki, Ban, Tatsuma, Wang, ZhiChao, Choi, Myoung Kwon, Kawamura, Takeshi, Negishi, Hideo, Nakasato, Makoto, Lu, Yan, Hangai, Sho, Koshiba, Ryuji, Savitsky, David, Ronfani, Lorenza, Akira, Shizuo, Bianchi, Marco E., Honda, Kenya, Tamura, Tomohiko, Kodama, Tatsuhiko, Taniguchi, Tadatsugu

NATURE 462 ( 7269 ) 99 - 103 2009.11

Research paper (scientific journal), Accepted,  ISSN  0028-0836

• Access to Document (DOI)

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, Ivaylo I., Atarashi, Koji, Manel, Nicolas, Brodie, Eoin L., Shima, Tatsuichiro, Karaoz, Ulas, Wei, Dongguang, Goldfarb, Katherine C., Santee, Clark A., Lynch, Susan V., Tanoue, Takeshi, Imaoka, Akemi, Itoh, Kikuji, Takeda, Kiyoshi, Umesaki, Yoshinori, Honda, Kenya, Littman, Dan R.

CELL 139 ( 3 ) 485 - 498 2009.10

Research paper (scientific journal), Joint Work, Accepted,  ISSN  0092-8674

• Access to Document (DOI)