Chikuma, Shunsuke

写真a

Affiliation

School of Medicine, Department of Microbiology and Immunology （Shinanomachi）

Position

Associate Professor (Non-tenured)

Related Websites
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Career 【 Display / hide 】

  • 2001.04
    -
    2006.03

    University of California San Francisco, Postdoctoral Researcher

  • 2006.04
    -
    2015.03

    Kyoto University Graduate School of Medicine, Assistant Professor

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Academic Background 【 Display / hide 】

  • 1991.04
    -
    1997.03

    Hokkaido University, Department of Veterinary Medicine

    University, Graduated

  • 1997.04
    -
    2001.03

    Hokkaido University, Graduate School of Medicine

    Graduate School, Completed, Doctoral course

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Academic Degrees 【 Display / hide 】

  • 博士（医学）, Hokkaido University, Coursework, 2001.03

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Licenses and Qualifications 【 Display / hide 】

  • DVM: Doctor Veterinary Medicine

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Research Areas 【 Display / hide 】

  • Life Science / Immunology

  • Life Science / Medical biochemistry

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Research Keywords 【 Display / hide 】

  • Cnacer Immunology

  • Allergy

  • Immune Regulation

  • Immune Tolerance

  • Autoimmunity

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Research Themes 【 Display / hide 】

  • Immune regulation by Immuno-inhibotory receptors, 

    1997.04
    -
    Present

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Proposed Theme of Joint Research 【 Display / hide 】

  • Ｔ細胞の人為的制御による、がん免疫の増強法、あるいはアレルギー、自己免疫疾患の制御法開発

    Interested in joint research with other research organizations (including universities, etc.)

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Books 【 Display / hide 】

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Papers 【 Display / hide 】

  • Efficacy and safety of anti-PD-1 antibody (Nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer.

    Hamanishi, Junzo, Mandai, Masaki, Ikeda, Takafumi, Minami, Manabu, Kawaguchi, Atsushi, Matsumura, Noriomi, Abiko, Kaoru, Baba, Tsukasa, Yamaguchi, Ken, Ueda, Akihiko, Kanai, Masashi, Mori, Yukiko, Matsumoto, Shigemi, Murayama, Toshinori, Chikuma, Shunsuke, Morita, Satoshi, Yokode, Masayuki, Shimizu, Akira, Honjo, Tasuku, Konishi, Ikuo

    JOURNAL OF CLINICAL ONCOLOGY 32 （ 15 ） 2772 - 2779 2014.05

    Research paper (scientific journal),  ISSN  0732-183X

  • Pathogenesis of autoreactive Th17 cells is driven by homeostatic cytokines stimulated by commensal microbiota

    Chikuma, Shunsuke, Takahashi, Hayato, Amagai, Masayuki, Yoshimura, Akihiko

    CYTOKINE 100   29 - 30 2017.12

    Research paper (scientific journal),  ISSN  1043-4666

  • Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells

    Okada, Masahiro, Chikuma, Shunsuke, Kondo, Taisuke, Hibino, Sana, Machiyama, Hiroaki, Yokosuka, Tadashi, Nakano, Miyako, Yoshimura, Akihiko

    CELL REPORTS 20 （ 5 ） 1017 - 1028 2017.08

    Research paper (scientific journal),  ISSN  2211-1247

  • Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy

    Kondo, Taisuke, Morita, Rimpei, Okuzono, Yuumi, Nakatsukasa, Hiroko, Sekiya, Takashi, Chikuma, Shunsuke, Shichita, Takashi, Kanamori, Mitsuhiro, Kubo, Masato, Koga, Keiko, Miyazaki, Takahiro, Kassai, Yoshiaki, Yoshimura, Akihiko

    NATURE COMMUNICATIONS 8   457 - 469 2017.05

    Research paper (scientific journal),  ISSN  2041-1723

  • Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy

    Chikuma, Shunsuke, Kanamori, Mitsuhiro, Mise-Omata, Setsuko, Yoshimura, Akihiko

    CANCER SCIENCE 108 （ 4 ） 574 - 580 2017.04

    Research paper (scientific journal),  ISSN  1349-7006

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Papers, etc., Registered in KOARA 【 Display / hide 】

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Research Projects of Competitive Funds, etc. 【 Display / hide 】

  • 肝内Ｔ細胞の自己認識による「功」の解明

    2023.04
    -
    2025.03

    学術変革領域研究(A), Principal investigator

  • アバタセプト抵抗性「しつこい」記憶T細胞を除去する方法の探索

    2022.06
    -
    2024.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 挑戦的研究（萌芽）, Principal investigator

  • 内在性レトロウイルス抑制因子による、がん免疫寛容機構の基盤研究

    2022.04
    -
    2025.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, 基盤研究(B), Principal investigator

  • 自己免疫疾患の発症・非発症を規定する特異点の検出

    2021.04
    -
    2023.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas, Principal investigator

  • 自己反応性Th17ヘルパーＴ細胞の長期生存機構の解析

    2019.04
    -
    2022.03

    MEXT,JSPS, Grant-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Principal investigator

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Courses Taught 【 Display / hide 】

  • IMMUNOLOGY

    2023

  • IMMUNOLOGY

    2022

  • IMMUNOLOGY

    2021

  • IMMUNOLOGY

    2020

  • IMMUNOLOGY

    2019

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Courses Previously Taught 【 Display / hide 】

  • 免疫学

    Keio University

    2018.04
    -
    2019.03
    , 

    Spring Semester, Lecture, Outside own faculty (within Keio), 110people

  • 免疫学実習

    Keio University

    2018.04
    -
    2019.03
    , 

    Laboratory work/practical work/exercise, Within own ｆaculty, 110people

  • 大学院修士課程「医学概論」　免疫学

    Keio University

    2018.04
    -
    2019.03
    , 

    Lecture, Within own ｆaculty, 15people

  • 免疫学

    Keio University

    2017.04
    -
    2018.03
    , 

    Spring Semester, Laboratory work/practical work/exercise

  • 免疫学

    Keio University

    2017.04
    -
    2018.03
    , 

    Spring Semester

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Educational Activities and Special Notes 【 Display / hide 】

  • 免疫学実習

    2015
    -
    Present

    , Device of Educational Contents

  • 免疫学

    2015
    -
    Present

    , Device of Educational Contents

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Memberships in Academic Societies 【 Display / hide 】

  • 日本分子生物学会, 

    2015
    -
    Present

  • 日本免疫学会, 

    2006
    -
    Present
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Committee Experiences 【 Display / hide 】

  • 2013
    -
    Present

    評議員, 日本免疫学会

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