佐田 みずき (サタ ミズキ)

Sata, Mizuki

写真a

所属(所属キャンパス)

医学部 衛生学公衆衛生学教室 (信濃町)

職名

助教(有期)

経歴 【 表示 / 非表示

  • 2012年12月
    -
    2021年03月

    茨城県立健康プラザ, 客員研究員

  • 2016年04月
    -
    継続中

    筑波大学, 医学医療系社会健康医学, 客員研究員

  • 2018年04月
    -
    継続中

    慶應義塾大学, 医学部衛生学公衆衛生学, 助教

  • 2018年05月
    -
    2022年03月

    大阪大学大学院, 医学系研究科社会医学講座公衆衛生学, 特任研究員

  • 2019年02月
    -
    継続中

    大阪がん循環器病予防センター, 特別研究員

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学歴 【 表示 / 非表示

  • 2012年04月
    -
    2014年03月

    大阪大学大学院, 医学系研究科, 医科学専攻

    大学院, 修了, 修士

  • 2014年04月
    -
    2018年03月

    大阪大学大学院, 医学系研究科, 医学専攻

    大学院, 単位取得退学, 博士

学位 【 表示 / 非表示

  • 博士(医学), 大阪大学, 2019年03月

 

研究分野 【 表示 / 非表示

  • ライフサイエンス / 衛生学、公衆衛生学分野:実験系を含む (疫学・予防医学)

  • ライフサイエンス / 衛生学、公衆衛生学分野:実験系を含まない (疫学・予防医学)

 

論文 【 表示 / 非表示

  • Accumulated unhealthy behaviours and insomnia in Japanese dwellers with and without cardiovascular risk factors: a cross-sectional study.

    Kato S, Harada S, Iida M, Kuwabara K, Sugiyama D, Takeuchi A, Sata M, Matsumoto M, Kurihara A, Hirata A, Okamura T, Takebayashi T

    BMJ open (BMJ open)  12 ( 4 ) e052787 2022年04月

    査読有り

     概要を見る

    OBJECTIVES: To date, the association between accumulated unhealthy behaviours and insomnia in individuals stratified according to the presence or absence of major cardiovascular risk factors is unclear. This study aimed to examine the effect of accumulated unhealthy behaviours on insomnia in Japanese dwellers. DESIGN: Cross-sectional study. SETTING: Baseline data between April 2012 and March 2015. PARTICIPANTS: Our study used cross-sectional data among Japanese aged 35-74 years in a rural community (N=9565), the attendees of annual municipal or work site health check-up programmes. MAIN OUTCOME MEASURES: Insomnia was assessed by Athens Insomnia Scale, which was set at 6 points and greater; other scales were given. Participants were categorised into three groups by their number of unhealthy behaviours (no exercise habit, smoking, alcohol drinking, skipping breakfast and obesity): 0-1, 2-3, 4 or more. The association between accumulated unhealthy behaviours and insomnia was estimated by logistic regression analysis. Further analysis was done after stratification of cardiovascular risk factors assessed by anthropometrics and clinical biochemistry measurements. RESULTS: The overall prevalence of insomnia was 13.3% for men and 19.3% for women. Men with unhealthy behaviour factors were more likely to have insomnia after adjusting for potential confounders, compared with the least unhealthy group (trend p=0.013). Women with four or more unhealthy behaviour factors were more likely to have insomnia, compared with the lowest groups (OR 1.175, 95% CI 1.077 to 1.282). Insomnia has an association with the unhealthy behaviours among men without cardiovascular risk factors (lowest groups: OR 1.133, 95% CI 1.037 to 1.238, trend p=0.026). Women without hypertension were more likely to have suspected insomnia, compared with the lowest group (OR 1.215, 95% CI 1.101 to 1.341). CONCLUSION: The results showed accumulated unhealthy behaviours were associated with increased risk of insomnia in Japanese dwellers. For healthy population without cardiovascular risk factors, unhealthy behaviours should be considered as background conditions for insomnia.

  • Trends in Prevalence, Treatment, and Control of Hypertension According to 40-Year-Old Life Expectancy at Prefectures in Japan from the National Health and Nutrition Surveys

    Sata M., Okamura T., Nishi N., Kadota A., Nakamura M., Kondo K., Okami Y., Kitaoka K., Ojima T., Yoshita K., Miura K.

    Nutrients (Nutrients)  14 ( 6 )  2022年03月

    査読有り

     概要を見る

    The prevalence of hypertension has been decreasing in Japan due to improved medical treatment and a decrease in dietary salt intake. However, disparities in the prevalence, treatment, and control of hypertension are expected to occur in different regions. This study aimed to investigate the trends in the prevalence, treatment, and control of hypertension at the prefectural level of life expectancy among Japanese population. We used data from the National Health and Nutrition Survey and analysed the individual survey information of individuals aged 40–69 years by dividing it into six terms, i.e., 1995–1997, 1999–2001, 2003–2005, 2007–2009, 2012, and 2016. Prefectures were classified into four groups according to their 40-year-old life expectancy in 2000. Outcome values were standardised to the population by 10-year age groups in 2010, and they were tested by two-way analysis of variance according to six terms and life expectancies. The prevalence of hypertension tended to decrease, especially among women, whereas the treatment and control tended to improve from the first to the sixth period in both men and women. The prevalence and treatment of hypertension in men with longer life expectancy tended to be lower than that in other groups, and there was no obvious difference in the control. In women, there were no obvious differences in the prevalence, treatment, or control. Reducing the prevalence of hypertension by improving lifestyle factors, such as high salt intake in each prefecture with a relatively short life expectancy, may be important to resolve the disparity in life expectancy among prefectures.

  • Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction

    Wang H., Lu H., Zhang X.M., Goto K.i., Kobayashi E., Yoshida Y., Adachi A., Matsutani T., Iwadate Y., Mine S., Machida T., Sata M., Yamagishi K., Iso H., Sawada N., Tsugane S., Kamitsukasa I., Wada T., Aotsuka A., Sugimoto K., Takizawa H., Kashiwado K., Shin H., Tomiyoshi G., Nakamura R., Shinmen N., Kuroda H., Xu A., Hiwasa T.

    BMC Neurology (BMC Neurology)  21 ( 1 ) 274 2021年12月

    研究論文(学術雑誌), 共著, 査読有り

     概要を見る

    Background: Ischemic stroke, including transient ischemic attack (TIA) and acute-phase cerebral infarction (aCI), is a serious health problem in the aging society. Thus, this study aimed to identify TIA and aCI biomarkers. Methods: In 19 patients with TIA, candidate antigens recognized by serum IgG autoantibodies were screened using a human aortic endothelial cell cDNA library. Through amplified luminescent proximity homogeneous assay-linked immunosorbent assay (AlphaLISA), serum antibody levels against the candidate antigens were examined in healthy donor (HD), TIA, and aCI cohorts (n = 285, 92, and 529). The plasma antibody levels in the Japan Public Health Center-based Prospective Cohort Study (1991–1993) were also examined. Results: The candidate antigens were aldolase A (ALDOA) and fumarate hydratase (FH). In AlphaLISA, patients with TIA or aCI had higher anti-ALDOA antibody (ALDOA-Ab) and anti-FH antibody (FH-Ab) levels than the HDs (P < 0.05). In a multivariate logistic regression analysis, the ALDOA-Ab (odds ratio [OR]: 2.46, P = 0.0050) and FH-Ab (OR: 2.49, P = 0.0037) levels were independent predictors of TIA. According to the case–control study, the ALDOA-Ab (OR: 2.50, P < 0.01) and FH-Ab (OR: 2.60, P < 0.01) levels were associated with aCI risk. In a correlation analysis, both ALDOA-Abs and FH-Abs were well associated with hypertension, coronary heart disease, and habitual smoking. These antibody levels also correlated well with maximum intima–media thickness, which reflects atherosclerotic stenosis. Conclusions: ALDOA-Abs and FH-Abs can be novel potential biomarkers for predicting atherosclerotic TIA and aCI.

  • Prediction of Lifetime Risk of Cardiovascular Disease Deaths Stratified by Sex in the Japanese Population.

    Imai Y, Mizuno Tanaka S, Satoh M, Hirata T, Murakami Y, Miura K, Waki T, Hirata A, Sairenchi T, Irie F, Sata M, Ninomiya T, Ohkubo T, Ishikawa S, Miyamoto Y, Ohnishi H, Saitoh S, Tamakoshi A, Yamada M, Kiyama M, Iso H, Sakata K, Nakagawa H, Okayama A, Ueshima H, Okamura T, Evidence for Cardiovascular Prevention From Observational Cohorts in Japan (EPOCH‐Japan) Research Group *.

    Journal of the American Heart Association (Journal of the American Heart Association)  10 ( 23 ) e021753 2021年11月

    共著, 査読有り

     概要を見る

    BACKGROUND: Lifetime risk is an informative estimate for driving lifestyle and behavioral changes especially for young adults. The impact of composite risk factors for cardiovascular disease on lifetime risk stratified by sex has not been investigated in the Japanese population, which has a much lower mortality of coronary heart disease compared with the Western population. We aimed to estimate lifetime risk of death from cardiovascular disease attributable to traditional risk factors. METHODS AND RESULTS: We analyzed pooled individual data from the Evidence for Cardiovascular Prevention from Observational Cohorts in a Japanese cohort study. A modified Kaplan– Meier approach was used to estimate the remaining lifetime risk of cardiovascular death. In total, 41 002 Japanese men and women with 537 126 person-years of follow-up were included. The lifetime risk at the index-age of 45 years for those with optimal risk factors (total cholesterol <4.65 mmol/L, systolic blood pressure <120 mm Hg, diastolic blood pressure <80 mm Hg, absence of diabetes, and absence of smoking habit) was lower compared with the highest risk profile of ≥2 risk factors (6.8% [95% CI, 0%–11.9%] versus 19.4% [16.7%– 21.4%] for men and 6.9% [1.2%–11.5%] versus 15.4% [12.6%–18.1%] for women). CONCLUSIONS: The magnitude and the number of risk factors were progressively associated with increased lifetime risk even in individuals in early adulthood who tend to have low short-term risk. The degree of established cardiovascular risk factors can be converted into lifetime risk. Our findings may be useful for risk communication in the early detection of future cardiovascular disease risk.

  • Breastfeeding in Infancy in Relation to Subsequent Physical Size: A 20-year Follow-up of the Ibaraki Children's Cohort Study (IBACHIL).

    Sata M, Yamagishi K, Sairenchi T, Irie F, Sunou K, Watanabe H, Iso H, Ota H

    Journal of epidemiology 2021年11月

    共著, 査読有り,  ISSN  0917-5040

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総説・解説等 【 表示 / 非表示

  • わが国における血清コレステロール値および脂質異常症の時代的推移

    佐田みずき,岡村智教

    日本循環器病予防学会誌 53   220 - 226 2018年

    記事・総説・解説・論説等(学術雑誌), 共著

  • 児童期におけるおやつの与え方が、22歳時の体格に与える影響:IBACHIL研究

    佐田みずき,山岸良匡,西連地利己,入江ふじこ,渡辺宏,磯博康,大田仁史

    日本循環器病予防学会誌 53   48 - 54 2017年

    記事・総説・解説・論説等(学術雑誌), 共著

研究発表 【 表示 / 非表示

  • 小中学生を対象とした生活習慣病予防のための健康副読本教育について~多機関が協働する、茨城県筑西市・秋田県井川町における副読本活用事業の紹介~.

    佐田みずき

    日本学校保健学会第67回学術大会 (名古屋) , 

    2021年11月

    シンポジウム・ワークショップ パネル(指名)

  • Impact of overweight on diabetes prevalence: 20-year trends in National Health and Nutrition Survey, Japan

    Mizuki Sata, Daisuke Sugiyama, Takumi Hirata, Saki Horie, Hidemi Takimoto, Tomonori Okamura

    The 22st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE2021) (Australia) , 

    2021年09月

    口頭発表(一般)

  • 都道府県単位の平均寿命別にみた国民健康・栄養調査結果における高血圧の推移

    佐田みずき, 岡村智教, 西信雄, 門田文, 中村美詠子, 近藤慶子, 北岡かおり, 尾島俊之, 由田克士, 三浦克之

    第57回日本循環器病予防学会学術集会 (名古屋) , 

    2021年06月

    口頭発表(一般)

  • 血清変性HDLと脳卒中発症との関連:鶴岡メタボロームコホート研究

    佐田みずき, 飯田美穂, 垣野明美, 原田成, 平田あや, 桑原和代, 杉山大典, 宇佐美陽子, 藤田佳子, 大木宏一, 伊澤良兼, 高橋愼一, 武林亨, 沢村達也, 岡村智教

    第45回日本脳卒中学会学術集会 (神奈川) , 

    2020年03月

    口頭発表(一般)

  • 茨城県が実施する小児期からの生活習慣病予防に関する研究(Ibaraki Children’s Cohort Study:IBACHIL)について

    佐田みずき

    第14回DOHaD疫学セミナー (東京) , 

    2020年02月

    公開講演,セミナー,チュートリアル,講習,講義等

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競争的研究費の研究課題 【 表示 / 非表示

  • 小児期からの減塩を中心とした生活習慣病予防教育法の開発と評価に関する疫学研究

    2020年04月
    -
    2023年03月

    文部科学省・日本学術振興会, 科学研究費助成事業, 佐田 みずき, 若手研究, 補助金,  研究代表者

  • 幼児期から成人期に至る追跡研究による生活習慣病予防のエビデンス構築と教育への応用

    2019年
    -
    2020年03月

    文部科学省・日本学術振興会, 科学研究費助成事業, 佐田 みずき, 研究活動スタート支援, 補助金,  研究代表者

  • 乳幼児期から成人期に至る長期コホート研究による生活習慣病予防のエビデンス構築

    2016年04月
    -
    2018年03月

    特別研究員奨励費, 佐田みずき, 補助金,  研究代表者

受賞 【 表示 / 非表示

  • 第12回日本循環器病予防学会奨励賞

    2021年06月, 日本循環器病予防学会, 12歳時における児の健康に関する親の意識・行動が児の10年後までの喫煙経験に与える影響:IBACHIL研究

    受賞区分: 国内学会・会議・シンポジウム等の賞

  • Young Investigator's Award最優秀賞 第6回日本循環器病予防学会予防医学賞

    2016年06月, 日本循環器病予防学会, 児童期におけるおやつの与え方が、22歳時の体格に与える影響:IBACHIL研究

    受賞区分: 国内学会・会議・シンポジウム等の賞

 

担当授業科目 【 表示 / 非表示

  • 公衆衛生学Ⅱ

    2022年度

  • 公衆衛生学Ⅰ

    2022年度

  • 衛生学Ⅰ

    2022年度

  • 衛生学Ⅱ

    2022年度

  • 地域保健学

    2022年度

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担当経験のある授業科目 【 表示 / 非表示

  • 医学統計・医療情報

    慶應義塾大学

    2018年04月
    -
    2019年03月

    秋学期, その他, 実習・実験

  • 公衆衛生学(調査研究)

    慶應義塾大学

    2018年04月
    -
    2019年03月

    秋学期, その他, 実習・実験

 

所属学協会 【 表示 / 非表示

  • 日本学校保健学会, 

    2021年10月
    -
    継続中
  • 日本アルコール・アディクション医学会, 

    2018年04月
    -
    継続中
  • 動脈硬化学会, 

    2018年04月
    -
    継続中
  • 日本産業衛生学会, 

    2018年04月
    -
    継続中
  • 日本衛生学会, 

    2018年04月
    -
    継続中

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