Obata, Rika

写真a

Affiliation

Faculty of Letters (Hiyoshi)

Position

Assistant Professor (Non-tenured)/Research Associate (Non-tenured)/Instructor (Non-tenured)

External Links

Matters concerning Career Achievements 【 Display / hide

  • 2016.11

    キラルな有機化合物の合成と構造の解析-Hitoshi Research Portfolio 2016

 

Books 【 Display / hide

  • 天然物化学−植物編

    OBATA RIKA, アイピーシー, 2007.02

    Scope: 第3章 植物由来の天然有機化合物の合成 第3節 リグナン,ネオリグナン

Papers 【 Display / hide

  • Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging

    Masahiro Kiyama, Satoshi Iwano, Satoshi Otsuka, Shijia W. Lu, Rika Obata, Atsushi Miyawaki, Takashi Hirano, Shojiro A.Maki

    Tetrahedron 74 ( 6 ) 652 - 660 2017.11

    Research paper (scientific journal), Joint Work, Accepted,  ISSN  0040-4020

  • Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

    Daisuke Yasuda, Akihiro Yuasa, Rika Obata, Mao Nakajima, Kyoko Takahashi, Tomoyuki Ohe, Yoshinobu Ichimura, Masaaki Komatsu, Masayuki Yamamoto, Riyo Imamura, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Tadahiko Mashino

    Bioorganic and Medicinal Chemistry Letters (ELSEVIER)  27 ( 22 ) 5006 - 5009 2017.11

    Research paper (scientific journal), Joint Work, Accepted

  • Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein inter- action inhibitors and their inhibitory activity

    Daisuke Yasuda, Mao Nakajima, Akihiro Yuasa, Rika Obata, Kyoko Takahashi, Tomoyuki Ohe, Yoshinobu Ichimura, Masaaki Komatsu, Masayuki Yamamoto, Riyo Imamura, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Tadahiko Mashino

    Bioorganic and Medicinal Chemistry Letters (ELSEVIER)  26 ( 24 ) 5956 - 5959 2016.10

    Research paper (scientific journal), Joint Work, Accepted,  ISSN  0960-894X

  • p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

    Tetsuya Saito, Yoshinobu Ichimura, Keiko Taguchi, Takafumi Suzuki, Tsunehiro Mizushima, Kenji Takagi, Yuki Hirose, Masayuki Nagahashi, Tetsuro Iso, Toshiaki Fukutomi, Maki Ohishi, Keiko Endo, Takefumi Uemura, Yasumasa Nishito, Shujiro Okuda, Miki Obata, Tsuguka Kouno, Riyo Imamura, Yukio Tada, Rika Obata, Daisuke Yasuda, Kyoko Takahashi, Tsutomu Fujimura, Jingbo Pi, Myung-Shik Lee, Takashi Ueno, Tomoyuki Ohe, Tadahiko Mashino, Toshifumi Wakai, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Hozumi Motohashi, Satoshi Waguri, Tomoyoshi Soga, Masayuki Yamamoto, Keiji Tanaka, Masaaki Komatsu

    Nature Communications 7 2016.06

    Research paper (scientific journal), Joint Work, Accepted

  • Multicolor bioluminescence obtained using firefly luciferin

    Masahiro Kiyama, Ryohei Saito, Satoshi Iwano, Rika Obata, Haruki Niwa, Shojiro A. Maki

    Current Topics in Medicinal Chemistry 16 ( 24 ) 2648 - 2655 2016

    Research paper (scientific journal), Joint Work, Accepted

display all >>

Papers, etc., Registered in KOARA 【 Display / hide

display all >>

Reviews, Commentaries, etc. 【 Display / hide

  • Caution in an Experiment of Electroless Nicckel Plating on Glass

    OBATA RIKA

    慶應義塾大学日吉紀要 自然科学 (慶應義塾大学)  63   15 - 25 2018.03

    Rapid communication, short report, research note, etc. (bulletin of university, research institution), Joint Work

  • What the Rf means in Paper Chromatography

    OBATA RIKA

    慶應義塾大学日吉紀要 自然科学 (慶應義塾大学)  60   7 - 15 2016.09

    Rapid communication, short report, research note, etc. (bulletin of university, research institution), Joint Work

  • Traffic signal reaction and decoloration of indigo carmine in an aqueous solution

    OBATA RIKA

    慶應義塾大学日吉紀要 自然科学 (慶應義塾大学)  59   21 - 33 2016.03

    Rapid communication, short report, research note, etc. (bulletin of university, research institution), Joint Work

  • 無電解めっきとフォトレジストを用いた鏡の作成

    OBATA RIKA

    慶應義塾大学日吉紀要 自然科学 (慶應義塾大学)  52   19 - 35 2012.09

    Rapid communication, short report, research note, etc. (bulletin of university, research institution), Joint Work

  • バルマーランプのスペクトルとスピロピラン化合物のフォトクロミズム

    OBATA RIKA

    慶應義塾大学日吉紀要 自然科学 (慶應義塾大学)  52   1 - 18 2012.09

    Rapid communication, short report, research note, etc. (bulletin of university, research institution), Joint Work

display all >>

Presentations 【 Display / hide

  • Cathodic Reduction of Acetophenone Using a Boron-Doped Diamond

    Kenshin Nakahara, Keisuke Naba, Rika Obata, Tsuyoshi Saitoh, Shigeru Nishiyama, Takashi Yamamoto, Yasuaki Einaga

    German Japanese Symposium on Electrosynthesis 2017 (GJSE-7) (Mainz, Germany) , 

    2017.09

    Poster presentation

  • Innovation of New Luciferin Analog for in vivo Optical Imaging

    Ryohei Saito, Masahiro Kiyama, Nobuo Kitada, Rika Obata, Rei Morimitsu, Haruki Niwa, Shojiro Maki

    World molecular Imaging Congress 2017 (Philadelphia, PA, USA) , 

    2017.09

    Poster presentation

  • SYNTHESIS AND BIOLUMINESCENCE OF HETEROCYCLIC ANALOGUES OF FIREFLY LUCIFERIN

    Rika Obata, N. Kitada, Shojiro A. Maki

    17th Asian Chemical Congress & 19th General Assembly of FACS (Melbourune, Australia) , 

    2017.07

    Poster presentation

  • ナフタレン骨格を有する選択的Keap-1-リン酸化p62阻害剤の創製研究

    湯浅章弘,安田大輔、大江知之、小畠りか、高橋恭子、小松雅明、一村義信、 山本雅之、今村理世、小島宏建、岡部隆義、長野哲雄,増野匡彦、

    第34回メディシナルケミストリーシンポジウム (つくば国際会議場) , 

    2016.12

    Poster presentation

  • Development of novel inhibitors for Keap1-Nrf2 and Keap1-p62 protein-protein interaction.

    Daisuke Yasuda, Akihiro Yuasa, Mao Nakajima, Takeo Yoshida, Rika Obata, Kyoko Takahashi, Tomoyuki Ohe, Yoshinobu Ichimura, Masaaki Komatsu, Masayuki Yamamoto, Riyo Imamura, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Tadashi Mashino

    The Society for Redox Biology and Medicine's 23rd Annual Meeting (SFRBM2016) (San Francisco, CA, USA) , 

    2016.11

    Poster presentation

display all >>

Research Projects of Competitive Funds, etc. 【 Display / hide

  • キラルな有機化合物の合成と構造の解析

    2014.04
    -
    2015.03

    Keio University, 自然科学研究教育センター 研究プロジェクト, Shigeru Ohba, Research grant, Coinvestigator(s)

  • ホタルルシフェラーゼ発光メカニズムの解明

    2014.04
    -
    2015.03

    Keio University, Keio Gijuku Academic Development Funds, Rika Obata, Research grant, Principal investigator

  • Synthesis and antibacterial activity of cyclic isodityrosine tripeptides (Pacifichem 2005)

    2005.12

    財団法人テルモ科学技術振興財団, 国際交流・出張助成金 2005年度後期, Research grant, Principal investigator

  • 生物活性を有する環状イソジロシン化合物の開発と応用

    2005.12
    -
    2006.03

    JST, シーズ育成試験, Rika Obata, Principal investigator

  • 環状イソジチロシン化合物の合成研究

    2005.04
    -
    2006.03

    Keio University, Keio Gijuku Academic Development Funds, Rika Obata, Research grant, Principal investigator

display all >>

Works 【 Display / hide

  • 科学探究ゼミナール2005 テーマ:「紅茶を飲むとなぜ眠れない?-カフェインの精製」担当

    OBATA RIKA

    2005.08

    Other, Single

Intellectual Property Rights, etc. 【 Display / hide

  • Naphthoquinone derivatives and G1 phase progression inhibitors, bactericides, imipenem activity enhancers, infectious disease inhibitors, etc., containing them.

    Date applied: JP2008201687A  2008.09 

    Patent, Joint

  • Preparation of cyclic isodityrosine derivatives having an imipenem-potentiating effect and a cholesteryl ester formation inhibiting activity.

    Date applied: WO2006054396A1  2006.05 

    Patent, Joint

  • Imine derivative and amide derivative

    Date applied: WO2005094805 A1  2004.04 

    Patent, Joint

  • Preparation of 4-O-demethylepipodophyllotoxin glycosides as antitumors.

    Date applied: EP455159A1  1991.11 

    Patent, Joint

  • 4′-デメチルエピポドフイロトキシングリコシド類

    Date applied: 平3-97100  1991.04 

    Date announced: 平5-92987  1993.04 

    Patent, Joint

display all >>

 

Courses Taught 【 Display / hide

  • LABORATORY IN SCIENCE

    2024

  • ADVANCED STUDY OF NATURAL SCIENCE 2

    2024

  • ADVANCED STUDY OF NATURAL SCIENCE 1

    2024

  • SCIENCE AND THE ENVIRONMENT1

    2024

  • LABORATORY IN SCIENCE

    2023

display all >>

Courses Previously Taught 【 Display / hide

  • Chemistry for life sciences

    Keio University

    2017.04
    -
    2018.03

    Spring Semester, Lecture

    GIC

  • Chemistry for life sciences

    Keio University

    2017.04
    -
    2018.03

    Autumn Semester, Lecture

    GIC

  • Chemistry for life sciences

    Keio University

    2016.04
    -
    2017.03

    Autumn Semester, Lecture

    GIC

  • Chemistry for life sciences

    Keio University

    2016.04
    -
    2017.03

    Spring Semester, Lecture

    GIC

 

Memberships in Academic Societies 【 Display / hide

  • The Society of Synthetic Organic Chemistry, Japan

     
  • The Chenmical Society of Japan

     
  • The Pharmaceutical Society of Japan

     
  • American Chemical Society

     

Committee Experiences 【 Display / hide

  •  

    会員, 有機合成化学協会

  •  

    会員, 日本化学会

  •  

    会員, 日本薬学会

  •  

    会員, アメリカ化学会

  •  

    Member, The Chenmical Society of Japan

display all >>