日本語
KEIO UNIVERSITY 
Faculty of Pharmacy 
Department of Pharmacy 

Associate Professor 
Matsushita Maiko 

 

Link to J-GLOBAL(Japanese Only) ]

Career
慶応義塾大学医学部内科学教室助手  2000/04-2006/06 
米国スローンケタリング記念癌研究所研究員  2001/04-2004/03 
慶応義塾大学医学部先端医科学研究所助手  2006/07-2010/03 
慶応義塾大学薬学部専任講師  2010/04-2014/03/31 
慶應義塾大学薬学部准教授  2015/04/01-Present 

Academic Background
Keio University  Faculty of Medicine  1995/03  Graduated 
Keio University  Graduate School, Division of Medicine  Doctoral course  2000/03  Completed 

Academic Degrees
医学  Keio University  2001/09 

Research Areas
Immunology 
General Internal Medicine (includes Psychosomatic Medicine) 
Hematology 
Oncology 

Research Themes
Development of novel immunotherapy against cancer  2010/04/01-Present 

Research Achievements (Original Articles and Commentaries)
Research paper (scholarly journal)  Joint  Immunomodulatory effects of drugs for effective cancer immunotherapy.  Matsushita M,Kawaguchi M.  Journal of Oncology  ID 8653489  2018/10 
Research paper (scholarly journal)  Joint  A novel derivative (GTN024) from a natural product, komaroviquinone, induced the apoptosis of high-risk myeloma cells via reactive oxygen production and ER stress.  Okayama M, Kitabatake S, Sato M, Fujimori K, Ichikawa D, Matsushita M, Suto Y, Iwasaki G, Yamada T, Kiuchi F, Hirao M, Kunieda H, Osada M, Okamoto S, Hattori Y  Biochem Biophys Res Commun  505/ 3, 787-793  2018/10 
Joint  Anticancer Drug Prescription Patterns in Japan: Future Directions in Cancer Therapy  Shoyo Shibata,Maiko Matsushita,Yoshimasa Saito,Takeshi Suzuki  Therapeutic Innovation & Regulatory Science  2018/03/05 
Joint  Optimal Anti-cancer Drug Profiles for Effective Penetration of the Anti-cancer Drug Market by Generic Drugs in Japan  Shoyo Shibata,Maiko Matsushita,Yoshimasa Saito,Takeshi Suzuki  Therapeutic Innovation & Regulatory Science  2017/12/26 
Research paper (scholarly journal)  CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients.  Matsushita M,Ozawa K, Suzuki T, Nakamura M, Nakano N, Kanchi S, Ichikawa D, Matsuki E, Sakurai M, Karigane D, Kasahara H, Tsukamoto N, Shimizu T, Mori T,Nakajima H, Okamoto S, Kawakami Y, Hattori Y.  Blood Cancer J.  7/ 9, e601.  2017/09/01 
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Research Achievements (Oral/Poster Presentations)
Poster presentation  Elucidation of the IMiDs-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells.  60th AMERICAN SOCIETY of HEMATOLOGY Annual Meeting and Exposition.  2018/12/03 
Poster presentation  Immunomodulatory Effects of Proteasome Inhibitors in Multiple Myeloma.  60th AMERICAN SOCIETY of HEMATOLOGY Annual Meeting and Exposition.  2018/12/01 
Oral presentation(general)  プロテアソーム阻害薬の免疫原性細胞死による免疫調節機能  第80回日本血液学会学術集会  2018/10/14 
Oral presentation(general)  新規天然化合物コマロビキノン化合物の抗骨髄腫効果および構造展開  第80回日本血液学会学術集会  2018/10/14 
Poster presentation  多発性骨髄腫のIMIDs抵抗性メカニズムの解明  第77回日本癌学会学術集会  2018/09/27 
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Research Achievements (Intellectual Property Rights)
Patent  フェニルフタルイミド修飾体及びそれを有効成分とする医薬組成物  2016-207402  2016/10/21 
Patent  化合物もしくはその薬理学的に許容される塩、抗腫瘍剤、又は活性酸素産生剤  2016-031897  2016/02/23  2017-149658  2017/08/31 
Patent  ペプチド、樹状細胞、細胞傷害性T細胞、白血病ワクチン、及び白血病受動免疫療法剤  2013-194119  2013/09/19  2015-71543  2015/04/16  6204130  2017/09/08 
Patent  がん免疫療法  2012-132288  2012/06/11  2013-256454(P2013-256454A)  2013/12/26  5984113  2016/08/12 
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Awards
日本骨髄腫学会奨励賞  新規ホメオボックス蛋白由来抗原を用いた多発性骨髄腫に対する複合的免疫治療法の開発  2015/05/16 
日本白血病研究基金一般研究賞  新規癌抗原を標的とした多発性骨髄腫に対する免疫治療法の開発  2013/11/09 
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