日本語
KEIO UNIVERSITY 
Faculty of Pharmacy 
Department of Pharmaceutical Sciences 

Associate Professor 
HIGASHIBAYASHI Shuhei 

Research Areas
Organic chemistry 

Research Achievements (Original Articles and Commentaries)
Research paper (scholarly journal)  Synthesis of trilobatin from naringin via prunin as the key intermediate: acidic hydrolysis of the -rhamnosidic linkage in naringin under improved conditions  Kurahayashi, Kazuki, Hanaya, Kengo, Higashibayashi, Shuhei, Sugai, Takeshi  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  82/ 9, 1463-1467  2018  0916-8451  10.1080/09168451.2018.1482455 
Research paper (scholarly journal)  Synthesis of oroxylin A starting from naturally abundant baicalin  Fujita, Rie, Hanaya, Kengo, Higashibayashi, Shuhei, Sugai, Takeshi  HETEROCYCLES  97, 1165-1174  2018  10.3987/COM-18-S(T)59 
Research paper (scholarly journal)  Synthesis of fisetin and 2,4,6-trihydroxydihyrochalcone 4-O--neohesperidoside based on site-selective deacetylation and deoxygenation  Tsunekawa, Ryuji, Hanaya, Kengo, Higashibayashi, Shuhei, Sugai, Takeshi  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  82/ 8, 1316-1322  2018  0916-8451  10.1080/09168451.2018.1467263 
Research paper (scholarly journal)  Tris(2-hydroxyphenyl)triazasumanene: bowlshaped excited-state intramolecular proton transfer (ESIPT) fluorophore coupled with aggregation-induced enhanced emission (AIEE)  Patcharin Kaewmati, Yumi Yakiyama, Hiroyoshi Ohtsu, Masaki Kawano, Setsiri Haesuwannakij, Shuhei Higashibayashi, Hidehiro Sakurai  MATERIALS CHEMISTRY FRONTIERS  2, 514-519  2018  10.1039/c7qm00530j 
Research paper (scholarly journal)  Formal total synthesis of (-)-hamigeran B from a chemo-enzymatically prepared building block with quaternary chiral center  Kazuaki Kuwata, Rie Fujita, Kengo Hanaya, Shuhei Higashibayash, Takeshi Sugai  TETRAHEDRON  74, 740-745  2018 
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Research Achievements (Oral/Poster Presentations)
Oral presentation(general)  生物活性物質合成に有用な、リパーゼが触媒する位置・官能基選択的反応  日本農芸化学会2019年度大会  2019/03/24 
Poster presentation  配糖体糖鎖の効率よい加水分解を利用した希少フラボノイドの合成研究  日本薬学会第139年会  2019/03/20 
Poster presentation  BCRPを介した3’,4’-ジメトキシフラボン類の抗がん剤耐性克服作用  日本薬学会第139年会  2019/03/20 
Poster presentation  1,3-ジカルボニル化合物の不斉還元における Chiralscreen® OH の有効性  第20回生体触媒化学シンポジウム  2018/12/12 
Oral presentation (invited/special)  Lipase-catalyzed site-selective deacetylation of sterically hindered polyphenol acetates and its application to the synthesis of bioactive natural products  第20回生体触媒化学シンポジウム  2018/12/12 
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Awards
有機合成化学奨励賞  おわん型π共役分子バッキーボウルの合成  2012 
日本化学会第90春季年会「若い世代の特別講演会」  C3対称バッキーボウルの液相合成法の開発  2010 
日本化学会第87春季年会優秀講演賞  キラルバッキーボウルの合成研究  2007 
天然物化学談話会奨励賞  非環状天然有機化合物の立体配置決定法Universal NMR Databaseの開発  2005 
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Memberships in Academic Societies
日本薬学会 
日本化学会 
有機合成化学協会 
基礎有機化学会 
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