日本語
KEIO UNIVERSITY 
Faculty of Pharmacy 
Department of Pharmaceutical Sciences 

Senior Assistant Professor / Assistant Professor 
MORIWAKI Yasuhiro 

Career
大阪府立成人病センター研究所  日本学術振興会特別研究員  2002/04/01-2003/03/31 
理化学研究所 脳科学総合研究センター  日本学術振興会特別研究員  2003/04/01-2003/08/31 
理化学研究所 脳科学総合研究センター  研究員  2003/09/01-2005/03/31 
共立薬科大学  助手  2005/04/01-2007/03/31 
共立薬科大学  助教  2007/04/01-2008/03/31 
慶應義塾大学  薬学部  助教  2008/04/01-2012/03/31 
米国 DUKE大学  Department of Immunology  研究員  2009/10/01-2010/09/30 
慶應義塾大学  薬学部  専任講師  2012/04/01-Present 

Academic Background
Nara Institute of Science and Technology  Graduate School, Division of Biological Science  Doctoral course  2003/03/24  Completed 

Research Achievements (Original Articles and Commentaries)
Research paper (scholarly journal)  Joint  Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1.  Matsuura R. Kaji H, Tomioka A, Sato T, Narimatsu H, Moriwaki Y, Misawa H, Imai K, Tsuji S.  Sci Rep.  8, 14251  2018/09/24  10.1038/s41598-018-32534-8 
Research paper (scholarly journal)  Joint  Dissociation of blood-brain barrier disruption and disease manifestation in an aquaporin-4-deficient mouse model of amyotrophic lateral sclerosis.  Watanabe-Matsumoto S, Moriwaki Y, Okuda T, Ohara S, Yamanaka K, Abe Y, Yasui M, Misawa H.  Neurosci Res.  133, 48-57  2018/08  10.1016/j.neures.2017.11.001. 
Research paper (scholarly journal)  Joint  SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosome.  Moriwaki Y*, Ohno Y, Ishii T, Takamura Y, Kita Y, Watabe K, Sango K, Tsuji S, Misawa H.  PLoS One.  13/ 6, e0199829  2018/06/28  10.1371/journal.pone.0199829. 
Research paper (scholarly journal)  Joint  Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes.  Komine O, Yamashita H, Fujimori-Tonou N, Koike M, Jin S, Moriwaki Y, Endo F, Watanabe S, Uematsu S, Akira S, Uchiyama Y, Takahashi R, Misawa H, Yamanaka K.  Cell Death Differ.  2018/03/22  10.1038/s41418-018-0098-3. 
Research paper (scholarly journal)  Joint  Expression and Function of the Cholinergic System in Immune Cells.  Fujii T, Mashimo M, Moriwaki Y, Misawa H, Ono S, Horiguchi K, Kawashima K.  Front Immunol.  8, 1085  2017/09/06  10.3389/fimmu.2017.01085 
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Research Achievements (Oral/Poster Presentations)
Poster presentation  Innate immune adaptor TRIF confers neuroprotection in ALS mice by eliminating abnormal astrocytes.  48th Annual Meeting, Society for Neuroscience  2018/11/07 
Poster presentation  Regulation of antigen-presenting cell (APC)-dependent CD4+ T cell differentiation by α7 nicotinic acetylcholine receptors on both APC and CD4+ T cells.  48th Annual Meeting, Society for Neuroscience  2018/11/05 
Oral presentation(general)  内在性神経毒類似タンパク質によるニコチン受容体調節の生理的役割の解明.  第33回平成29年度喫煙科学研究財団助成研究発表会  2018/07/24 
Poster presentation  Roles for α7 nicotinic acetylcholine receptors on naïve CD4+ T cells and antigen-presenting cells in regulation of differentiation.  18th World Congress of Basic and Clinical Pharmacology  2018/07/05 
Poster presentation  ニコチン性アセチルコリン受容体に対する内在性モジュレーターLy6Hの調節作用.  第138回日本薬理学会関東部会  2018/03/10 
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Memberships in Academic Societies
北米神経科学学会  2015/10/01-Present 
日本薬学会  2011/04/01-Present 
日本神経科学学会  2007/04/01-Present 
日本薬理学会  2005/04/01-Present 
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  About KOARA(KeiO Associated Repository of Academic resources)(Japanese Only)