日本語
KEIO UNIVERSITY 
Faculty of Pharmacy 
Department of Pharmacy 

Professor 
TAMURA Hiroomi 

 

Link to J-GLOBAL(Japanese Only) ]

Academic Background
The University of Tokyo  Faculty of Pharmaceutical Science  1978/03/31  Graduated 
The Graduate School, University of Tokyo  Graduate School of Pharmaceutical Sciences  Division of Biological Pharmaceutics  Doctoral course  1983/03/31  Completed 

Academic Degrees
Doctor of Pharmacy  The University of Tokyo  1983/03/31 

Academic Awards
日本薬学会東海支部 平成6年度 学術奨励賞受賞  1994/11 
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Licenses and Qualifications
the pharmacist license in Japan 

Research Areas
Biological System Pharmaceutical Science 
Environmental Pharmaceutical Science 
Eating habits 

Research Themes
Relationship between inhibition of estrogen sulfoconjugation by coffee component and prevention of life-style related dideases by coffee intake.  2008-2010 
Effects of vitamin C on the conjugation reactions in the human colon carcinoma Caco-2 cells. 
Induction of neurosteriod biosynthesis in human glial GI-1 cells by retinoic acid. 

Research Achievements (Books)
Dexamethasone Suppresses Neurosteroid Biosynthesis in Human Glial Cells via Cross-Talk with Vitamins A and D. in Horizons in Neuroscience Research. Volume 24  TAMURA Hiroomi  Chapter 8, pp. 137-148  Nova Science Publishers  2016/04/01  978-1-63484-325-6 
Coffee in Health and Disease Prevention.  TAMURA Hiroomi  Chapter 61. Effects of Coffee on Estrogen Sulfation in Human Colon Carcinoma Caco-2 Cells.  Academic Press  2014/11/03 
コーヒーはお好きですか?.  田村悦臣.  慶應義塾  2014/02 
薬学領域の食品衛生化学(長澤一樹、川崎直人編).  田村悦臣.  37-93  廣川書店, 東京  2013/03 
薬学用語辞典.  田村悦臣.  1-449  東京化学同人, 東京  2012/03 
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Research Achievements (Original Articles and Commentaries)
Research paper (scholarly journal)  Joint  Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides.  TAMURA Hiroomi  Biosci. Biotechnol. Biochem.  2018/10/13  10.1080/09168451.2018.1530970 
Research paper (scholarly journal)  Joint  Roasted coffee reduces beta-amyloid production by increasing proteasomal beta-secretase degradation in human neuroblastoma SH-SY5Y cells.  TAMURA Hiroomi  Mol. Nutr. & Food Res.  Wily  2018/08/25  10.1002/mnfr.201800238 
Joint  A 5-hydroxyoxindole derivative attenuates LPS-induced inflammatory responses by activating the p38-Nrf2 signaling axis.  TAMURA Hiroomi  Biochem. Pharmacol.  155, 182-197  2018/06/22  10.1016/j.bcp.2018.06.021 
Research paper (scholarly journal)  Joint  Taxodione induces apoptosis in BCR-ABL-positive cells through ROS generation.  TAMURA Hiroomi  Biochem. Pharmacol.  154, 357-372  2018/06/01  doi:10.1016/j.bcp.2018.05.018 
Research paper (scholarly journal)  Joint  Effect of hesperetin derivatives on the development of selenite‑induced cataracts in rats.  TAMURA Hiroomi  Molecular Medicine Reports  18, 1043-1050  2018/03/22  10.3892/mmr.2018.9045. 
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Research Achievements (Oral/Poster Presentations)
Oral presentation (invited/special)  コーヒーによる認知症予防効果について  認知症予防学会 第6回学術講演会  2017/02/26 
Poster presentation  5-Hydroxyoxindole誘導体のLPSシグナル経路阻害による抗炎症作用  第89回 日本生化学会大会  2016/09/26 
Poster presentation  慢性骨髄増殖性腫瘍に対するメトトレキサートの新しい作用機序  第89回 日本生化学会大会  2016/09/26 
Oral presentation(general)  本態性血小板血症の原因遺伝子産物JAK2V617F変異体によるTpoRのリン酸化を介した発がん誘導機構  第89回 日本生化学会大会  2016/09/26 
Poster presentation  コーヒー成分によるヒト神経芽細胞腫におけるβ-セクレターゼ発現の抑制効果  第89回日本生化学会大会  2016/09/25 
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Awards
平成28年度 義塾賞  コーヒーの生活習慣病予防効果の分子基盤の解析  2016/11/11 
日本薬学会東海支部学術奨励賞.  Bacillus cereus 由来スフィンゴミエリナーゼの構造と機能の解析  1994/07 
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Memberships in Academic Societies
International Society for Neurochemistry 
認知症予防学会 
日本神経化学会 
生薬学会 
日本生化学会 
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  Link to KOARA(Japanese Only) About KOARA(KeiO Associated Repository of Academic resources)(Japanese Only)
  About KOARA(KeiO Associated Repository of Academic resources)(Japanese Only)